2021, Number 07
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Ginecol Obstet Mex 2021; 89 (07)
Paraneoplastic dermatomyositis in the context of bilateral ovarian cancer: A case report and a literature review
Azcona-Sutil L, Cabezas-Palacios MN, Gutiérrez-Domingo Á, Barros-Tornay R, Polo A, Jiménez-Gallardo J, Rodríguez-Jiménez I
Language: Spanish
References: 13
Page: 561-566
PDF size: 205.04 Kb.
ABSTRACT
Background: Dermatomyositis, as a paraneoplastic syndrome, can be associated
with ovarian cancer 9 to 21.4% of the time. Due to the muscle involvement involved,
it is a major overshadowing in the morbidity of these patients. To identify the primary
tumor, it is necessary to have a high level of diagnostic suspicion, which means performing
complementary tests not yet clearly established.
Clinical case: A 62-year-old patient, with no known allergies, consulted due to the
appearance of a pruritic rash of 20 days of evolution in the facial region, neck, neckline
and external face of the limbs accompanied by myalgia and some asthenia. Examination
revealed erythematous maculopapular exanthema in the mainly photoexposed body
regions and papules in the dorsal region of the metacarpophalangeal joints. The definitive
anatomopathologic study reported: high-grade serous carcinoma with multinodular
solid pattern in the left ovary and high-grade serous carcinoma with multinodular
solid-papillary pattern in the right ovary; both adnexae with paratubal infiltration.
Conclusions: Establishing a correct and rapid diagnosis of dermatomyositis is
fundamental due to its strong association with occult neoplasms; this makes it decisive
to confirm the diagnosis and carry out an exhaustive extension study, especially in
high-risk patients, when faced with a patient with data of dermatomyositis.
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