medigraphic.com
Instituto Nacional de Neurología y Neurocirugía

2021, Number 2

<< Back Next >>

Arch Neurocien 2021; 26 (2)

Sleep quality, REM sleep behavior disorder and daytime sleepiness in adults with and without Parkinson's

Díaz-Pacheco A, Moo-Estrella J

Language: English
References: 37
Page: 20-25
PDF size: 265.83 Kb.


ABSTRACT

In Parkinson's disease (PD), poor sleep quality and sleep disorders are central part of the nonmotor symptoms. The aim was to compare sleep quality (SQ), REM sleep behavior disorder (RBD) and excessive daytime sleepiness (EDS) among adults with and without Parkinson's disease (PD). A second objective was to know the relationship of SQ and RBD with EDS in patients with PD. Method. Sixty adults (38% women, mean age 66.7±8.11 years), 50% with PD diagnosis and 50% healthy controls, Instruments: Epworth Sleepiness Scale, Sleep Quality Pittsburgh Index and REM Behavioral Disorder Sleep Questionnaire, which was designed for this study. Results. Differences were found in SQ (PD = 9.90 ±4.47 vs Control group = 7.23 ±4.71, t = 2.25, p = .028), and the percentage of cases with symptoms of RBD (PD = 30%, control group = 6.7%, ji2 = 5.455, p = .020). No differences were found in EDS (PD = 7.43 ±5.46 vs Control group = 6.50 ±5.28, t = .673, p = .504). According to the linear regression analysis, the increase in EDS was not associated with SQ, EDS was only associated with RBD. Conclusion, the PD group presents a poor sleep quality and a higher prevalence of RBD symptoms. EDS did not differ between adults with and without PD. However, RBD was associated with an increase in EDS in the PD group.


REFERENCES

  1. Cross-Alcalá LE, Vázquez-Castellanos JL. Prevalence of certain neurological diseases in the city of Tepatitlán, Jalisco, Mexico. Rev Mex Neuroci. 2002; 3: 71-6. http://previous.revmexneurociencia. com/wp-content/uploads/2014/07/Nm0022-01.pdf

  2. Gwinn K, David K, Swanson-Fischer C, Albin R, Hillaire-Clarke C, Sieber B, et al. Parkinson's disease biomarkers: perspective from the NINDS Parkinson's disease biomarkers program. Biomarkers in Medicine. 2017;11(6):451-473. Doi: 10.2217/ bmm-2016-0370

  3. Koychev I, Okai D. Cognitive–behavioural therapy for nonmotor symptoms of Parkinson's disease: a clinical review. Evid Based Mental Health. 2017; 20(1):15-20. Doi: 10.1136/ eb-2016-102574

  4. Bellosta-Diago E, Lopez-del Val L, Santos-Lasaosa S, et al. Association between REM sleep behaviour disorder and impulse control disorder in patients with Parkinson's disease. Neurología (english edition). 2017; 32(8):494-99. Doi:10.1016/j. nrleng.2016.02.007

  5. Hsiao Y, Chen Y, Tseng C, Wu L, Perng D, Chen Y et al. Sleep disorders and an increased risk of Parkinson's disease in individuals with non-apnea sleep disorders: a population-based cohort study. J Sleep Res. 2017; 26(5):623-28. Doi: 10.1111/jsr.12545

  6. Chahine L, Amara A, Videnovic A. A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015. Sleep Med Rev. 2017; 35:33-50. Doi: 10.1016/j.smrv.2016.08.001

  7. Sateia. International classification of sleep disorders, 3rd edn. highlights and modifications. Chest. 2014; 146(5):1387-94. Doi: 10.1378/chest.14-0970

  8. Matar E, Lewis S. REM sleep behaviour disorder: not just a bad dream. Med J Australia. 2017; 207(6):262-8. Doi: 10.5694/ mja17.00321

  9. Zhang X, Sun X, Wang J, Tang L, Xie A. Prevalence of rapid eye movement sleep behavior disorder (RBD) in Parkinson’s disease: a meta and meta-regression analysis. Neurological Sciences. 2017; 38(1):163-170. Doi: 10.1007/s10072-016-2744-1

  10. Knie B, Mitra M, Logishetty K, Chaudhuri K. Excessive daytime sleepiness in patients with Parkinson's disease. CNS Drugs. 2011; 25(3):203-12. Doi: 10.2165/11539720-000000000-00000

  11. Shen Y, Huang J, Li J, Liu C. Excessive daytime sleepiness in Parkinson’s disease. Chin Med J. 2018; 131(8):974-81. Doi: 10.4103/0366-6999.229889

  12. Brodsky M, Godbold J, Roth T, Olanow C. Sleepiness in Parkinson's disease: A controlled study. Mov Disord. 2003; 18(6):668-72. Doi: 10.1002/mds.10429

  13. Xiang Y, Xu Q, Sun Q, Wang Z, Tian Y, Fang L, et al. Clinical Features and correlates of excessive daytime sleepiness in Parkinson's disease. Fron Neurol. 2019; 10. https://Doi. org/10.3389/fneur.2019.00121

  14. Tholfsen L, Larsen J, Schulz J, Tysnes O, Gjerstad M. Development of excessive daytime sleepiness in early Parkinson disease. Neurology. 2015; 85(2):162-8. Doi: 10.1212/ WNL.0000000000001737

  15. Sandoval-Rincon M, Alcalá-Lozano R, Herrera-Jimenez I, Jimenez-Genchi A. Validation epwort sleepiness scale in mexican population. Gac Med Mex. 2013;149(4):409-16. https://www. medigraphic.com/pdfs/gaceta/gm-2013/gm134d.pdf

  16. Hita-Contreras F, Martínez-López E, Latorre-Román P, Garrido F, Santos M, Martínez-Amat A. Reliability and validity of the spanish version of the Pittsburgh sleep quality index (psqi) in patients with fibromyalgia. Rheumatol Int. 2014; 34(7):929-36. Doi: 10.1007/s00296-014-2960-z

  17. Lebrun C, Gély-Nargeot MC, Bayard S. Insomnia comorbid to Parkinson's disease part I: epidemiology, assessment, and related factors. Geriatr Psychol Neuropsychiatr Vieil. 2020; 1, 18(3):321-30. English. Doi: 10.1684/pnv.2020.0874.

  18. Gjerstad M D, Wentzel-Larsen T, Aarsland D, Larsen J P. Insomnia in Parkinson’s disease: frequency and progression over time. J Neurol Neurosurg Psychiatry. 2007; 78(5): 476-479. Doi: 10.1136/jnnp.2006.100370

  19. Stefani A, Högl B. Sleep in Parkinson’s disease. Neuropsychopharma. 2020; 45:121–8. https://Doi.org/10.1038/s41386-019-0448-y

  20. González-Naranjo JE, Alfonso-Alfonso M, Grass-Fernandez D, Morales-Chacón LM, et al. Analysis of sleep macrostructure in patients diagnosed with Parkinson's disease. Behav Sci (Basel). 2019; 8, 9(1):6. Doi: 10.3390/bs9010006.

  21. Jasti DB, Mallipeddi S, Apparao A, et al. Quality of sleep and sleep disorders in patients with parkinsonism: A polysomnography based study from rural South India. J Neurosci Rural Pract. 2018; 9(1): 92-9. Doi: 10.4103/jnrp.jnrp_189_17.

  22. Shafazand S, Wallace DM, Arheart KL, Vargas S, et al. Insomnia, Sleep quality, and quality of life in mild to moderate Parkinson's disease. Ann Am Thorac Soc. 2017; 14(3): 412-9. Doi: 10.1513/ AnnalsATS.201608-625OC.

  23. Zhu K, van Hilten JJ, Marinus J. The course of insomnia in Parkinson's disease. Parkinsonism and related disorders. 2016; 33, 51-57. Doi: 10.1016/j.parkreldis.2016.09.010

  24. Tholfsen LK, Larsen JP, Schulz J, Tysnes OB, Gjerstad MD. Changes in insomnia subtypes in early Parkinson disease. Neurol. 2017; 88(4), 352-8. Doi: 10.1212/WNL.0000000000003540

  25. Lysen TS, Darweesh SKL, Ikram MK, Luik AI, Ikram MA. Sleep and risk of parkinsonism and Parkinson's disease: a population-based study. Brain. 2019; 142(7):2013-22. Doi: 10.1093/brain/awz113.

  26. Moo Estrella J. Sueño y Pakinson. En Entendiendo al paciente con enfermedad de Parkinson. Salazar Ceballos, et al. 2018; (8):103-119. https://www.researchgate.net/ publication/350372741_Sueno_y_Parkinson

  27. Nodel M, Ukraintseva Y, Yakhno N. Syndrome of rapid eye movement sleep behavior disorder and Parkinson's disease in nocturia. Nevrologii zhurnal imeni SS Korsakova i psikhiatrii. 2017;117(9):15-20. Doi: 10.17116/jnevro20171179115-20

  28. Kim J, Criaud M, Cho S, Díez-Cirarda M, Mihaescu A, Coakeley S, et al. Abnormal intrinsic brain functional network dynamics in Parkinson’s disease. Brain. 2017; 140(11):2955-67. Doi: 10.1093/brain/awx233

  29. Xie D, Shen Q, Zhou J, Xu Y. Non-motor symptoms are associated with REM sleep behavior disorder in Parkinson's disease: a systematic review and meta-analysis. Neurol Sci. 2020; 42(1):47- 60. Doi: 10.1007/s10072-020-04769-9.

  30. Rolinski M, Szewczyk-Krolikowski K, Tomlinson PR, Nithi K, Talbot K, Ben-Shlomo Y, et al. REM sleep behaviour disorder is associated with worse quality of life and other non-motor features in early Parkinson's disease. J Neurol Neurosurg Psychiatry. 2014; 85:560–6. Doi: 10.1136/jnnp-2013-306104.

  31. Arnulf I, Neutel D, Herlin B, Golmard JL, et al. Sleepiness in Idiopathic REM sleep behavior disorder and Parkinson disease. Sleep. 2015; 38(10):1529–35. https://Doi.org/10.5665/ sleep.5040

  32. Liguori C, Mercuri NB, Albanese M, Olivola E, Stefani A, Pierantozzi M. Daytime sleepiness may be an independent symptom unrelated to sleep quality in Parkinson's disease. J Neurol. 2019; 266(3):636-41. Doi:10.1007/s00415-018-09179-8.

  33. Patel N, LeWitt P, Neikrug AB, Kesslak P, Coate B, Ancoli-Israel S. Nighttime sleep and daytime Sleepiness improved with pimavanserin during treatment of Parkinson's disease psychosis. Clin Neuropharmacol. 2018; 41(6):210-215. Doi: 10.1097/ WNF.0000000000000307.

  34. Naismith SL, Rogers NL, Mackenzie J, Hickie IB, Lewis SJ. The relationship between actigraphically defined sleep disturbance and REM sleep behaviour disorder in Parkinson's Disease. Clin Neurol Neurosurg. 2010; 112(5):420-3. Doi:10.1016/j. clineuro.2010.02.011.

  35. Dickson DW. Neuropathology of Parkinson disease. Parkinsonism Relat Disord. 2018; 46(S1):S30-S33. Doi:10.1016/j. parkreldis.2017.07.033.

  36. Avorn J, Schneeweiss S, Sudarsky LR, Benner J, Kiyota Y, Levin R, et al. Sudden uncontrollable somnolence and medication use in Parkinson disease. Arch Neurol. 2005; 62:1242–8. Doi: 10.1001/ archneur.62.8.1242.

  37. Paus S, Brecht HM, Köster J, Seeger G, Klockgether T, Wüllner U, et al. Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease. Mov Disord. 2003; 18:659-67. Doi: 10.1002/mds.10417




2020     |     www.medigraphic.com