García ACB, Guzmán PMG, Gallegos GAC, Sánchez VLRA

Language: Spanish
References: 8
Page: s73-75
PDF size: 135.77 Kb.

ABSTRACT

Chilblains or pernio are an acral erythematous or violaceous dermatosis. The etiology is idiopathic related to cold weather or secondary to some diseases, connective tissue diseases among them. Pernio is the second most frequent dermatosis related to SARS-CoV-2. The patients are usually pauci or asymptomatic with both negative PCR or serology tests. In a recent study with electronic microscopy, viral particles were observed in a skin biopsy, confirming the association with the virus. The prevalence of chilblains in Mexico is unknown, they tend to be rare because of the warm weather. Two cases are presented, of women from the third and fourth decades of life, with chilblains in hands and feet respectively, asymptomatic with COVID-19.

REFERENCES

1. Andina D, Noguera-Morel L, Bascuas-Arribas M, Gaitero-Tristán J, Alonso-Cárdenas JA, Escalada-Pellitero S et al. Chilblains in children in the setting of COVID-19 pandemic. Pediatr Dermatol. 2020; 37 (3): 406-411. doi: 10.1111/pde.14215.

2. Nyssen A, Benhadou F, Magnée M, André J, Koopmansch C, Wautrecht JC. Chilblains. Vasa. 2020; 49 (2): 133-140. doi: 10.1024/0301-1526/a000838.

3. Colmenero I, Santoja C, Alonso RM, Noguera-Morel L, Hernández-Martín A, Andina D et al. SARS-CoV-2 endothelial infection causes COVID-19 chilblains: histopathological, immunohistochemical and ultrastructural study of seven paediatric cases. Br J Dermatol. 2020; 183 (4): 729-737. doi: 10.1111/BJD.19327.

4. Freeman EE, McMahon DE, Lipoff JB, Rosenbach M, Kovarik C, Desai SR et al. The spectrum of COVID 19 associated dermatologic manifestations: an international registry of 716 patients from 31 countries. J Am Acad Dermatol. 2020; 83: 1118-1129. doi: 10.1016/j.jaad.2020.06.1016.

5. Galván CC, Catalá A, Carretero HP, Fernández NA, Rodriguez-Villa LI, Navarro FR et al. Classification of the cutaneous manifestation of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020; 29. doi: 10.1111/bjd.19163.

6. Le Cleach L, Dousset L, Assier H, Fourati S, Barbarot S, Boulard C et al. Most chilblains observed during the COVID-19 outbreak occur in patients who are negative for COVID-19 on polimerase chain reaction and serology testing. Br J Dermatol. 2020; 183 (5): 866-874. doi: 10.1111/bjd.19377.

7. Herman A, Peeters C, Verroken A, Tromme I, Tennstedt D, Marot L. Evaluation of chilblains as a manifestation of COVID-19 pandemic. JAMA Dermatol. 2020; 156 (9): 998-1003. doi: 10.1001/jamadermatol.2020.2368.

8. Mohan V, Lind R. Chilblains in COVID-19 infection. Cureus. 2020; 12 (7): e9245. doi: 10.7759/cureus.