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Revista de Endocrinología y Nutrición

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2002, Number 1

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Rev Endocrinol Nutr 2002; 10 (1)

Clinical usefulness of metabolic size

Meléndez G
Full text How to cite this article

Language: Spanish
References: 11
Page: 21-26
PDF size: 128.85 Kb.


Key words:

Metabolic size, body surface area, allometry, basal energy expenditure.

ABSTRACT

Advent of artificial nutrition into clinical settings during the past 30 years has impelled development of important new technologies. Use of parenteral paths for infusing energy substrates has saved lives whose otherwise would have died as consequence of starvation and malnutrition. However, methods currently in use for calculating patients’ energy requirements have not changed and at present we are still applying equations 82 years old. New generations of nutritionists are not aware of where these popular equations, such as the Harris-Benedict, were derived from and simply adopt them without a question, ignoring that there exist alternative methods for calculating basal energy expenditure, with functions including metabolic size, which have better physiologic modeling and precision, particularly in low weight, low height individuals.
The present review is a brief description of events about the origins and evolution of functions for calculating surface area, the allometric relation of energy expenditure among homeothermic animals, better known as metabolic size and basal energy expenditure; all these concepts are intimately related among each other and represent the fundamentals for energy requirement estimates, which is part of our current practice at the time we deal with patients bearing different nutritional pathologies.


REFERENCES

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  2. Harris JA, Benedict FG. A biometric study of basal metabolism in man. Washington. Carnegie Institution of Washington. Publication No. 279; 1919.

  3. Stigler SM. The history of statistics. The measurement of uncertainty before 1900. 1st ed. Harvard University Press; 1990.

  4. Fisher RA. The design of experiments. 4th ed. London: Oliver and Boyd; 1947.

  5. Kleiber M. The fire of life. Revised ed. New York (NY): Robert E. Krieger Publishing Company; 1975.

  6. Rubner M. The laws of energy consumption in nutrition. San Diego (CA): USA, Academic Press; 1982.

  7. Blaxter K. Energy metabolism in animals and man. 1st ed. Cambridge (MA): Cambridge University Press; 1989.

  8. Rivers JPW. Heat, life and energy. An introduction to thermal physiology. Handout for the master of science degree. Human Nutrition Department. London School of Hygiene and Tropical Medicine. University of London, October 1983.

  9. Wilkie DR. Metabolism and body size. In: Pedley TJ. Ed. Scale Effects in Animal Locomotion. Academic Press. 1977: p23-36.

  10. West GB, Brown JH, Enquist BJ. A general model for the origin of allometric scaling laws in biology. Science 1997; 276: 122-126.

  11. Calder WA. III. Scaling of physiological processes in homeothermic animals. Ann Rev Physiol 1981; 43: 301-322.




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Rev Endocrinol Nutr. 2002;10