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2021, Number 3

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Otorrinolaringología 2021; 66 (3)

Role of intratympanic gentamicin for management of Ménière’s disease

Ramírez-Arroyo G, Carrillo-Pacheco E
Full text How to cite this article

Language: Spanish
References: 9
Page: 220-228
PDF size: 222.76 Kb.


Key words:

Ménière’s disease, Vertigo, Gentamicin.

ABSTRACT

Background: Ménière’s disease is a clinical syndrome characterized by spontaneous vertigo attacks, associated with fluctuating neurosensorial hearing loss, tinnitus, and aural fullness. The diagnosis is based on the criteria proposed by the Barany Society. 10 to 20% of patients with Ménière’s disease have intractable vertigo, management alternatives in these cases are endolymphatic sac surgery, infiltration with intratympanic gentamicin, vestibular neurectomy, and labyrinthectomy.
Clinical case: A 62-year old female patient with bilateral Ménière’s disease presented with incapacitating vertigo that did not respond to lifestyle changes nor to treatment with betahistine, diuretics, or steroids. For management of intractable vertigo, the patient received intratympanic gentamicine in August, 2016. After the infiltration, the patient had not presented any vertigo crisis for 3 years and the phonemic discrimination has been stable. As part of a comprehensive medical care, she received vestibular rehabilitation, a hearing aid was adapted, and she received treatment by the psychiatry department. Multidisciplinary management improved quality of life in this patient.
Conclusions: This clinical case exemplifies the use of intratympanic gentamicin as a therapeutic alternative for intractable vertigo, even in the context of socially useful hearing.


REFERENCES

  1. Alexander TH, Harris JP. Current epidemiology of Meniere’s syndrome. Otolaryngol Clin North Am 2010; 43 (5): 965-70. http://dx.doi.org/10.1016/j.otc.2010.05.001.

  2. Lopez-Escamez JA, Carey J, Chung WH, Goebel JA, et al. Diagnostic criteria for Menière’s disease. J Vestib Res 2015; 25: 1-7.

  3. Sajjadi H, Paparella MM. Meniere’s disease. Lancet 2019; 372: 406-14. doi: 10.1016/S0140-6736(08)61161-7.

  4. Basura GJ, Adams ME, Monfared A, Schwartz SR, et al. Clinical Practice Guideline: Ménière’s Disease. Otolaryngol Head Neck Surg 2020; 162 (2_suppl): S1-55. doi: 10.1177/0194599820909438.

  5. Welling DB, Nagaraja HN. Endolymphatic mastoid shunt: A reevaluation of efficacy. Otolaryngol Neck Surg 2000; 122 (3): 340-5. doi: 10.1067/mhn.2000.101575.

  6. Flores-García MDL, De la Llata-Segura C, Cisneros-Lesser JC, Pane-Pianese C. Endolymphatic sac surgery for Ménière’s disease - Current opinion and literature review. Int Arch Otorhinolaryngol 2017; 21: 179-83. doi: 10.1055/s-0037-1599276.

  7. Perkins E, Rooth M, Dillon M, Brown K. Simultaneous labyrinthectomy and cochlear implantation in unilateral meniere’s disease. Laryngoscope Investig Otolaryngol 2018; 225-30. doi: 10.1002/lio2.163.

  8. Chia SH, Gamst AC, Anderson JP, Harris JP. Intratympanic gentamicin therapy for Ménière’s disease: A meta-analysis. Otol Neurotol 2004; 25 (4). doi: 10.1097/00129492- 200407000-00023.

  9. Martín-Sanz E, Esteban-Sánchez J, González-Juliao M, Zschaeck-Luzardo C, et al. Electrococleografía extratimpánica en la enfermedad de Ménière. Acta Otorrinolaringol Esp 2012; 63 (6): 421-8. DOI: 10.1016/j.otorri.2012.03.007.




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Otorrinolaringología. 2021;66