Blugerman G, Schavelzon D, Martínez L, Bonesana G, Chomyszyn A, Pontón A, Izurrategui N

Language: Spanish
References: 12
Page: 192-197
PDF size: 497.79 Kb.

ABSTRACT

The platelet-rich plasma (PRP) is obtained by small extraction of blood, centrifuged and processed, obtaining a gel that is a natural support and autologous of the fatty tissue for the trans- plant. It favours the formation of main extracellular matrix, collagen fibers and accelerates angiogenesis as it has been reported in bone tissues assays, as it promotes neovascularization and avoids the reabsorption of the fatty tissue in transplants.
The ideal combination is that of the rich platelet plasm (PRP) and fatty autologous, because it has been of great utility to restore atrophic defects of the subcutaneous facial tissue, to recover the facial aesthetic features. It has been also used in the body, to correct asymmetries, to stuff depressions, to increase volumes, to correct liposuction sequels or atrophic scars.
The factors of growth are polypeptids of amino acids that form a globular protein and that they belong to the group of the citokines. In different moments, these factors induce the proliferation, diferenciation and quimiotaxis in the target cells, macropahges and osteoblastos; and they also stimulate the angiogenesis.
The epithelial growth factor (EGF) was the first to be found with the capacity to induce proliferation in epidermal cultured cells and the platelet derived growth factor (PDGF) it is the one that is considered more potent for the repair of the wounds, and it is the first one to appear (before the 24 hours of the lesion). At the beginning they were obtained by bio-engineering methods and used in the treatment of burns and in post peelings.
Later due to the advances in odontology with dental implants new simple methods were developed, with the patient’s own blood. It is the centrifuged fraction corresponding to the platelet concentrate or platelet-rich plasma (PRP) that can activate with a minimum dose of chloride of calcium (to 10%) and produced a whitish clot very rich growth factors.
In these last two years in the Clínica B&S were carried out 450 procedures with autograft of fat associated to PRP. Of these procedures 340 were carried out for the treatment of facial defects and 110 cases for defects in the body, some of them associated to liposhifting.The combination of fatty liposuction under special technical conditions, added with PRP is allowing us to induce a restoration of the tissues facial or body defects PRP is a material 100% autologous, practically without risks. In our experience it increases and it improves the survival of the fatty implant at the same time that it improves the texture of the skin under which it is implanted.

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