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2020, Number 4

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Rev cubana med 2020; 59 (4)

Prognostic factors subclinical atherosclerosis in dyslipidemic patients

Herrera GA, González DD, Tamargo BTO, Soto MJ, Peña GY

Language: Spanish
References: 14
Page: 1-11
PDF size: 412.34 Kb.


ABSTRACT

Introduction: Subclinical atherosclerosis is a predictor of future vascular events and is diagnosed by imaging and biomarkers without any clinical manifestations.
Objective: To identify the prognostic factors that are associated with subclinical atherosclerosis in dyslipidemic patients.
Method: A cohort study was carried out at the Hermanos Ameijeiras Hospital in 1028 patients in the period from 2016 to 2019.
Results: The existence of atheroma plaque was 26.9%. There were significant differences related to smoking (30.0% vs 23.7%). In the lipid variables, the average of the LDLc values ​​is higher in patients with atheroma plaque and the CT/LDL ratio is higher in those without this alteration. Regarding the frequency of thickening of the intima-media complex greater than 1.0 mm, it was 37.1%. There were significant differences related to smoking (30.4% vs 22.4%) and the presence of HTA (56.7% vs 48.8%) in the lipid variables, the average of the HDLc values ​​is higher in the patients without an increase in the thickness of the intima-media complex and the CT/HDL elevation is greater in those with said alteration.
Conclusions: The factors that independently influence the probability of atheroma plaque formation are LDLc (elevated), age, triglycerides and male sex, and those that influence the probability of thickening of the intima-media complex. They are HDLc (low), smoking, and high blood pressure.


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