Munafó L, Quesada G

Language: Spanish
References: 10
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ABSTRACT

Tropical spastic paraparesis / HTLV-1-related myelopathy is a rare cause of chronic myelopathy caused by HTLV-1 retrovirus (human T-lymphocyte lymphotropic virus).
We present the case report of a 45-year-old female patient with upper motor neuron syndrome associated with 2-year history of bladder tenesmus. In whom it was possible to document hyperintense dorsal inflammatory medullary injury (T3-T4) on MRI of spine in association with anti HTLV-1 antibodies.

REFERENCES

1. Satoshi Nozuma and Steven Jacobson. Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis. Frontiers in Microbiology. April 2019 | Volume 10 | Article 885

2. Charles R. M. Bangham, Abelardo Araujo, Yoshihisa Yamano and Graham P. Taylor. HTLV 1 associated myelopathy/tropical spastic paraparesis. Nature reviews | disease primers 2015 Macmillan Publishers

3. Luis Cartier R. Paraparesia espástica progresiva asociada a HTLV-I en Chile: Estudio y seguimiento de 121 pacientes por diez años. Revista Chilena de Neuro-Psiquiatría 2009; 47 (1): 50-66

4. Unsong Oh, Steven Jacobson. Treatment of HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis: Toward Rational Targeted Therapy. Neurologic Clinics. 26 (2008) 781–797

5. Sonja Tattermusch y Charles R.M. Bangham. HTLV-1 infection: what determines the risk of inflammatory disease?. Trends in Microbiology, 2012; 20 (10) 494-500

6. Liliana Raulino Goncalvesa, Leopoldo Nelson Fernandes Barbosab, Paula Machado Ribeiro Magalhaesa, Pedro Augusto Sampaio Rocha-Filhoa. Characterization of cognitive performance and evaluation of quality of life among patients with HTLV-1. Clinical Neurology and Neurosurgery 160 (2017) 142–146

7. Yoshimi Enose-Akahata and Steven Jacobson. Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology (2019)

8. Ana Paula Silva Champsa, Valéria Maria de Azeredo Passosc, Guilherme Carvalhoa, Sandhi Maria Barretod, Carla Meirellesa, Paulo Caramelli.. Cognitive impairment in HTLV-1-associated myelopathy, proviral load and inflammatory markers. International Journal of Infectious Diseases. 2019; 84: 121- 126

9. Tracey A. Cho,Shamik Bhattacharyya. Approach to myelopathy. American Academy of Neurology. April 2018

10. Ariella L G Coler-Reilly, Tomoo Sato , Toshio Matsuzaki , Masanori Nakagawa, Masaaki Niino, Masahiro Nagai. Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study. Neurotherapeutics. 2017 Oct;14(4):1084-1094