Sánchez-Tadeo MT, Rodríguez-González BC, Haro-Ríos AJ, Montes-Aceves FJ, Avalos-Ramírez AG, Cabrales-Chávez S, Cárdenas-Membrila R

Language: Spanish
References: 12
Page: 185-190
PDF size: 549.99 Kb.

ABSTRACT

Myoepithelial carcinoma is a tumor of glandular origin with a very low incidence, it is characterized by the presence of myoepithelial cells and lack ductal diff erentiation. Most of them develop in salivary glands (60-80%), followed by breast, laryngeal, retroperitoneal and lung tissue. Myoepithelial carcinoma located exclusively in the dermis is extremely rare and usually presents as a skin condition with involvement of the eccrine and apocrine glands. We present the case of a 72-year-old female patient, with an elevenyear long evolution tumor. Th ree biopsies, cytology and immunohistochemical stains were performed to obtain a clinical-histopathological diagnosis. No criteria have been described histologically to classify them between malignant and benign. Th erefore, immunohistochemistry is performed, where most cutaneous myoepithelial carcinomas are reactive to AE1 / AE3, PAN-K (93%), S-100 protein (87%), calponin (86%), epithelial membrane antigen (63%) and glial fi brillary acidic protein (46%).

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