Medina-Castillo J, López-Villa NN, Jacobo-Torralba JA, Rentería-Manzanilla MM

Language: Spanish
References: 10
Page: 1087-1093
PDF size: 278.50 Kb.

ABSTRACT

Background: Brown tumors are osteolytic lesions occurring in 0.1% of all cases of hyperparathyroidism. In tertiary hyperparathyroidism, the parathyroid gland is not responding to the negative feedback signals, such as high serum calcium.
Clinical case: A 29-year-old woman with a history of chronic kidney disease, diagnosed in 2013, in replacement therapy since 2018. In 2019 patient was referred to the endocrinology department for moderate hypercalcemia. During the study protocol, two tumors compatible with brown tumors were detected, tertiary hyperparathyroidism was suspected, paratohormone levels in 2175 pg/mL, as well as parathyroid focus ultrasound reporting right parathyroid adenoma. Adenoma resection was performed, with a reduction in paratohormone, serum calcium and a marked decrease in brown tumors.
Conclusions: Brown tumors are one of the complications that occur in patients with bone mineral disease, which conditions high cardiovascular risk in the renal patient, so, we must monitor closely levels of paratohormone, calcium and phosphorus in this population.

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