medigraphic.com
SPANISH

Medicina Interna de México

Colegio de Medicina Interna de México.
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2021, Number 6

<< Back Next >>

Med Int Mex 2021; 37 (6)

Alpha-fetoprotein-producing hemangioma

Zapata-Olivares H, Reyes L, García F, De la Torre y Rendón FE, Álvarez-Kobayashi J, García-Samper MX
Full text How to cite this article

Language: Spanish
References: 10
Page: 1099-1102
PDF size: 197.23 Kb.


Key words:

Hemangioma, Cavernous hemangioma, Alpha-fetoprotein, Hepatocarcinoma.

ABSTRACT

Background: Cavernous hemangioma is the most common vascular hepatic lesion in adults, usually accompanied by tumor markers within normal ranges. However, isolated cases of patients with elevated alpha-fetoprotein have been documented, and it is necessary to be clear about the diagnostic approach to liver lesions, based on adequate complementary studies.
Clinical case: An 80-year-old female patient with tomographic finding of liver lesion associated with a history of clear cell renal carcinoma, performing an approach to rule out metastases, primary lesion or benign alteration. Hepatic lesion was approached with imaging and laboratory studies, referring a suggestive pattern tomography of hemangioma. However, due to the persistence elevation of alpha-fetoprotein reaching levels of up to 1210 ng/mL, MRI imaging was requested, reporting lesion compatible with hepatocarcinoma, undergoing the patient under ultrasound-guided biopsy resulting in cavernous hemangioma.
Conclusions: The evaluation of patients complemented with adequate studies is essential for a timely and accurate diagnosis.


REFERENCES

  1. Ishak KG, Anthony PP, Niederau C, Nakanuma Y. Mesenchymal tumours of the liver. In: Hamilton SR, Aaltonen LA, editors. World Health Organization Classification of Tumors. Pathology and Genetics of Tumours of the Digestive System. IARC Press; Lyon, France: 2000; 191-198.

  2. Ball D, Rose E, Alpert E. Alpha-fetoprotein levels in normal adults. Am J Med Sci 1992; 303 (3): 157-9. doi: 10.1097/00000441-199203000-00004.

  3. Karhunen PJ. Benign hepatic tumours and tumour like conditions in men. J Clin Pathol 1986; 39: 183-188. doi: 10.1136/jcp.39.2.183.

  4. Motta-Ramírez, Gómez-Pompermayer, Ortiz-León, Cohe- Yañez. Hemangioma hepático: Patrones de imagen por tomografía computada multidetector. Rev Sanid Milit Mex 2009; 63 (6): 280-285.

  5. Schumacker HB Jr. Hemangioma of the liver. Surgery 1942; 11:209-222.

  6. Wu J. Serum alpha-fetoprotein and its lectin reactivity in liver diseases: a review. Ann Clin Lab Sci 1990; 20: 98-105.

  7. Ball D, Rose E, Alpert E. Alpha-fetoprotein levels in normal adults. Am J Med Sci 1992; 303: 157-159. doi: 10.1097/00000441-199203000-00004

  8. Huan-Yu Wang, Liang Zhang, Jian Wu, Zi-Jian Zhang, Bao- Gang Peng, Li-Jian Liang, Qi Zhou. Adult hepatic cavernous hemangioma with highly elevated a-fetoprotein: A case report and review of the literature. Oncol Lett 2015; 9 (2): 637-640. doi: 10.3892/ol.2014.2769.

  9. European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. J Hepatol 2018; 69: 182-236. doi: 10.1016/j. jhep.2018.03.019.

  10. Elsayes KM, Kielar AZ, Chernyak V, Morshid A, et al. LI-RADS: a conceptual and historical review from its beginning to its recent integration into AASLD clinical practice guidance. J Hepatocell Carcinoma 2019; 6: 49-69. doi: 10.2147/JHC. S186239.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Med Int Mex. 2021;37