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2021, Number 4

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Enf Infec Microbiol 2021; 41 (4)

Vaccination in Down syndrome children

Baeza CJA, Juárez CCE, Reyes GU, Espinosa SMC, Guerrero BM, Reyes HKL, González OAM, Almonte DAE, Alonso PNC
Full text How to cite this article

Language: Spanish
References: 44
Page: 162-167
PDF size: 181.37 Kb.


Key words:

immune dysfunction, T lymphocytes, immunizations, congenital heart malformations, Down syndrome children.

ABSTRACT

Down syndrome children have high morbidity and mortality due to infectious diseases, especially of the respiratory tract, especially in the first five years of life, all due to immune dysfunctions of T lymphocytes associated with the syndrome and other factors such as: their functional neurological and behavioral disability and the coexistence in some cases of anomalies of the cardiac and respiratory systems mainly due to congenital pathologies, among others. This review is a proposal for specific immunizations for this risk group, and a review of each of the biologics indicated therein. It highlight avoid the missed opportunities and emphasizing the application of the booster dose given that the immunocellular response in them is incomplete.


REFERENCES

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Enf Infec Microbiol. 2021;41