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Organo Oficial de la Secretaria de Salud de Quintana Roo

2015, Number 31

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Salud Quintana Roo 2015; 8 (31)

Environmental and food risks in children and adolescents with diagnosis of leukemia in Tlaxcala

Flores-López G, Méndez-Hernández P, Cuacenetl-Jiménez JJR, Rojas-Lima E, Nava-Cruz CB, Mauricio-García JF, Cruz-Angulo MC

Language: Spanish
References: 21
Page: 12-16
PDF size: 217.00 Kb.


ABSTRACT

Objective: To analyze the association between environmental and food factors, with the risk of acute lymphoblastic leukemia (ALL) in children and adolescents in the State of Tlaxcala.
Materials and methods: A case-control, not matched, non-probability study was held in 89 patients from 4 to 20 years old with a diagnosis of ALL who reside in the State of Tlaxcala, Mexico. The research was conducted among the cases reported at the Children´s Hospital of Tlaxcala in the period 2008-2013. The instrument used was a questionnaire that assesses chronic exposures to toxic substances in the environment, previously used in Mexico.
Results: It was that found that in the group of cases the majority of the participants were men (67.3%), with an average age of 10.7 years. In the controls, 55.1% were women and the average age was of 10.9 years. In regard to the risk of ALL related to the exposure of the mother to cigarette smoke, children and adolescents whose mothers refer to have been exposed to cigarette smoke were 12.3 times more risk of ALL (95% CI; 2.5-59.4 p≤0. 002) than those whose mothers were not exposed. It was observed that the risk of ALL is 28.4 times higher in those who consume fruit occasionally, compared with those who consumed it often (95% CI; 8.9-90.5 p≤0. 000).
Conclusions:It is necessary to continue studying in greater depth the impact of environmental pollution and low consumption of antioxidants on development of ALL.


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