Alexánderson E

Language: Spanish
References: 12
Page: 527-530
PDF size: 47.59 Kb.

ABSTRACT

Myocardial blood flow quantification has become a challenge in current cardiology practice. Among nuclear techniques, single-photon emission computed tomography (SPECT) with Tl-201 or Tc-99m-Sestamibi is one of the most widely used, predominantly because of its availability. This method involves a semiquantitative analysis for regional myocardial blood flow. Positron emission tomography (PET) with ¹³N-ammonia is considered the most accurate non-invasive method for the quantification of myocardial blood flow and coronary flow reserve. The objective measurement of this flow values allow us to detect incipient coronary artery disease, which entails great value for patients without coronary lesions by angiography, but with cardiovascular risk factors (diabetes, hypertension, dislipidemia, smoking). Measurement of myocardial perfusion with ¹³N-ammonia PET help us to assess the physiologic significance of coronary lesions, even though, these are not associated to significant stenosis by angiography.

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