Mejía-García C

Language: Spanish
References: 0
Page: 75-84
PDF size: 176.53 Kb.

ABSTRACT

Background: Nowadays, the interest in vitamin D supplementation goes beyond its calcemic functions because deficiency in its concentrations has been related to immunological, gynecological and human reproductive diseases.
Objective: To review the most recent evidence in relation to the consequences of its deficiency in different alterations in the reproductive life of women and men.
Methodology: Retrospective trial based on the bibliographic search of articles relating vitamin D deficiency with the appearance of polycystic ovary syndrome, uterine myomatosis, endometriosis, ovarian reserve, male factor (in reproduction), assisted reproduction techniques, pregnancy, lactation, and menopause. The search was performed in PubMed and Google Scholar databases for articles published between 1999 and 2020.
Resultados: We found 108 articles and discarded 91 because they did not meet the inclusion criteria. Since the analysis was limited exclusively to the relationship of the appearance of diseases in women linked to alterations in reproductive life due to vitamin D deficiency, only 17 were analyzed.
Conclusions: In clinical practice, making decisions about different treatments is always difficult, and even more so when there is controversy about when, how, and how much. In general, it seems effective and safe to take vitamin D with the high-dose schedule, since it increases adherence to treatment due to its convenience and does not represent a greater risk of toxicity; it also allows prompt correction of serum concentrations of the vitamin, especially in patients in whom it is desired to reach the objective in a short time, such as women who will undergo reproductive treatment.