Zavaleta-Martínez M, Mendoza-Enciso E, Poletti-Vázquez DE

Language: Spanish
References: 0
Page: 185-192
PDF size: 272.25 Kb.

ABSTRACT

Background: Gangrenous pyoderma is an uncommon chronic dermatosis, secondary to the infiltration of neutrophils in the different layers of the skin, which causes the development of inflammatory and ulcerative lesions, usually multiple pustules with a violet border and purulent fundus. It is estimated that in up to 77% of cases, there is an underlying systemic disease, the majority of which are diseases with an autoimmune etiopathogenic background, so the diagnosis of gangrenous pyoderma must generate the intentional search for concomitant diseases, which may have implications prognosis in evolution and treatment.
Clinical case: A 29-year-old female patient with gangrenous pyoderma in whom the development of autoimmune hepatitis and primary subclinical hypothyroidism was documented, who had a rapid and favorable response to immunosuppressive treatment.
Conclusions: autoimmune hepatitis has been described in other case reports with favorable response to different immune treatment; however, association with autoimmune thyroid disease is even more scarce.