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2020, Number 3

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Invest Medicoquir 2020; 12 (3)

Necrobiosislipoídica

León GY, Alfonso SC
Full text How to cite this article

Language: Spanish
References: 13
Page:
PDF size: 540.53 Kb.


Key words:

necrobiosislipoídica, pentoxifilina.

ABSTRACT

Necrobiosis lipoídica, chronic granulomatous disease of unknown etiology, associates to systemic diseases like the type 2 diabetes mellitus, and autoimmune, like lupus erythematosus and the rheumatoid arthritis. Theyhavedescribedmultipletreatments, fromtopicalcorticosteroids to monoclonal antibodiesintralesionales. Wepresent a feminine, whitepatient's case, of 51 years of agewithpathological personal background of SpasmodicAsthma and of injuries in skin characterizedbythepresence of plateslocated in superior limbs and inferiors of over 10 years of evolution. There are no family record orstaffs of Diabetes Mellitus.


REFERENCES

  1. Wee SA, Possick P. Necrobiosis lipoidica. Dermatol Online J 2004;10(3):18.

  2. Fourati M, Marrak H, Fenniche S, Zakraoui H, Zghal M, Khayat O, et al. Necrobiosis lipoidica. Report of 4 cases and review of the literature. Tunis Med 2003; 81(6):428-31.

  3. Aslan E, Körber A, Grabbe S, Dissemond J. Successful therapy of ulcerated necrobiosis lipoidica non diabeticorum with cyclosporine A. Hautarzt. 2007 Apr 12. [Medline].

  4. Omugha N, Jones AM. The management of hard-to-heal necrobiosis with PROMOGRAN. Br J Nurs. 2003;12(15 Suppl): S14-20.

  5. Freinkal RK. Manifestaciones cutáneas de las enfermedades endocrinas. En: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF, eds. Dermatología en Medicina General. 4ta ed. Buenos Aires: Editorial Médica Panamericana; 1997:2199-2217.

  6. Tokura Y, Mizushima Y, Hata M, Takigawa M. Necrobiosis lipoidica of the glans penis. J Am Acad Dermatol. 2003; 49(5):921-4.

  7. Naschitz JE, Fields M, Isseroff H, Wolffson V, Yeshurun D. Unilateral necrobiosis lipoidica of the ischemic limb—a case report. Angiology. 2003;54(2):239-42.

  8. Mseddi M, Marrekchi S, Bouassida S, Meziou T, Boudaya S, Turki H, Zahaf A. Necrobiosis lipoidica - 3 case reports. Rev Med Liege. 2006;61(7-8):589-92.

  9. De Rie MA, Sommer A, Hoekzema R, Neumann HA. Treatment of necrobiosis lipoidica with topical psoralen plus ultraviolet A. Br J Dermatol. 2002;147(4):743-7.

  10. Basaria S, Braga-Basaria M. Necrobiosis lipoidica diabeticorum: response to pentoxiphylline. J Endocrinol Invest. 2003 Oct;26(10):1037-40.

  11. Nguyen K, Washenik K, Shupack J. Necrobiosis lipoidica diabeticorum treated with chloroquine. J Am Acad Dermatol. 2002;46: S34-6.

  12. Bum Kim. Extensive Pigmented Purpuric Dermatosis Successfully Treated with Pentoxifylline. Ann Dermatol 2012; 24 (3): 363-365. [volver a cita]

  13. Thornhill MH, Baccaglini L. A Randomized, Double-blind, Placebo-Controlled Trial of Pentoxifylline for Moon-Bum Kim. Extensive Pigmented Purpuric Dermatosis Successfully Treated with Pentoxifylline.




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Invest Medicoquir. 2020;12