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Instituto Nacional de Salud Pública

2022, Number 3

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salud publica mex 2022; 64 (3)

Neurotoxicity among petrochemical workers with low exposure indexes to organic solvents

Juárez-Pérez CA, Rodríguez-Jiménez A, Martínez-Santiago G, Mercado-Calderón FA, Trujillo-Reyes O, Aguilar-Madrid G, Cabello-López A

Language: Spanish
References: 26
Page: 290-298
PDF size: 281.66 Kb.


ABSTRACT

Objective. To estimate the neuropsychological performance and its association with exposure to organic solvents (OS) among petrochemical workers in Mexico. Materials and methods. Cross-sectional study including 203 workers: 102 exposed to OS and 101 non-exposed. Neuropsychological performance was evaluated with Neurobehavioral Core Test Battery. Exposure to OS was evaluated with the metabolites from exposure to toluene, xylenes and benzene. Results. Exposed workers presented with a worse performance in all tests (p‹0.05), except for Santa Ana test. This was corroborated with regression models; workers exposed to OS had a higher number of mistakes and performed the tests in longer time (p‹0.05), together with having greater odds of neurotoxicity symptoms (OR: 2.93; 95%CI: 0.96, 8.96). Conclusions. Occupational exposure to organic solvents, even at levels allowed by current Mexican standards, was related to an impaired neuropsychological performance.


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