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2022, Number 3

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Med Int Mex 2022; 38 (3)

Clinical and immunological characteristics of systemic lupus erythematosus applying the classification criteria of EULAR/ACR 2019

Renée SD, Mercado U
Full text How to cite this article

Language: Spanish
References: 12
Page: 507-513
PDF size: 188.39 Kb.


Key words:

Systemic lupus erythematosus, Antinuclear antibodies, Cutaneous lupus.

ABSTRACT

Objetivo: To describe the frequency and the clinical and immunological characteristics of systemic lupus erythematosus applying the 2019 EULAR/ACR classification criteria.
Materials and Method: A retrospective study was done describing the frequency and the clinical and immunological characteristics of patients with systemic lupus erythematosus care in the internal medicine and rheumatology service from 2014 to 2020. The cut-off points for the individual diagnosis of lupus was ≥ 10 points. The presence of antinuclear antibodies was mandatory.
Results: There were included 132 patients, 116 women and 16 men with a 7:1 ratio. The median age was 35 years (range: 12 to 58); 77% had arthritis, 71% leukopenia, 59% acute cutaneous lupus, 41% oral ulcers and 32% fever. Nephropathy was observed in 28%, determined by proteinuria or renal biopsy; in 13 cases the histopathological study revealed type III/IV nephritis and in one case type II/V nephritis (ISN/RPS); 78% had anti-DNA native and 20% anti-Sm/RNP. The decrease in complement was found in 22% of the cases.
Conclusions: The new classification criteria of EULAR/ACR 2019 for systemic lupus erythematosus are based on previous criteria, except for fever. All our patients fulfilled 10 or more points to meet the classification criteria.


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Med Int Mex. 2022;38