Cruz-Martínez E, Escobar-Mendoza E, Santana-García F, Urrutia-Ruíz M, Barragán-Pérez E, Espinoza-Montero R, Pérez-Ramírez M, Hernández-Aguilar J, Hernández-Hernández M, Garza-Morales S

Language: Spanish
References: 9
Page: 241-246
PDF size: 139.15 Kb.

ABSTRACT

Introduction. Möebius syndrome (MS) is a rare congenital disease of multifactorial etiology; VI and VII cranial nerves or their nucleus are involved in its clinical presentation, with facial diplegia and inability to abduct the eyes beyond the midline; other cranial nerves are also involved. As far as 90% of patients have normal intelligence. Objective: to describe the characteristics of seizure in children with MS and epilepsy.
Material and methods. A descriptive retrolective study of children with MS attended in the Hospital Infantil de Mexico Federico Gomez from 1994 to 2004. Clinical characteristics of seizures were determined.
Results. Thirty one patients with MS were analyzed; of these, 8 had epilepsy (25.8%), 2 cases (6.4%) partial epilepsy, 4 cases (12.9%) generalized epilepsy; one case (3.22%) with epilepsy plus and 1 case (3.22%) with infantile spasms. In 7 of 8 cases of epilepsy, the EEG was abnormal and there were multiple abnormalities in neuroimaging.
Conclusion. Epilepsy in children with MS is probably determined by other associated diseases, it is not the result of MS itself.

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