medigraphic.com
SPANISH

Revista Médica Sinergia

Revista Médica Sinergia
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2022, Number 07

<< Back Next >>

Revista Médica Sinergia 2022; 7 (07)

Bacterial vaginosis during pregnancy: last discoveries uptodate

Morelli MI, Gamboa MS
Full text How to cite this article

Language: Spanish
References: 19
Page:
PDF size: 159.64 Kb.


Key words:

bacterial vaginosis, pregnancy, vaginal discharge, dysbiosis.

ABSTRACT

Bacterial vaginosis is caused by an imbalance in the bacterial populations of the normal vaginal microbiota. Certain conditions in which hormonal variations occur, like pregnancy, can trigger this dysbiosis. This affection is asymptomatic in most cases, but it can manifest as a whitish malodorous vaginal discharge. Regarding its pathophysiology, the virulent factors of the pathogenic bacteria are responsible for the disruption of the vaginal microenvironment. Most of its risk factors are the same as the ones for adquiring a sexual transmited disease, eventhough low vitamin D levels correlate too. Its diagnosis can be made based upon clinical, histopathological or molecular findings, but the latest tools are rapid tests based on enzymes detection. In relation to its treatment, the majority of the time, the consensus favors giving it to pregnant patients with symptoms. It is not the case with the asymptomatic ones, where it is unclear if it helps or not.


REFERENCES

  1. Kortekaas J, Kazemier B, Keulen J, Bruinsma A, Mol B, Vandenbussche F et al. Risk of adverse pregnancy outcomes of late‐ and postterm pregnancies in advanced maternal age: A national cohort study. Acta Obstetricia et Gynecologica Scandinavica [Internet]. 2020 [cited Apr 30, 2022];99(8):1022-1030. Doi: https://doi.org/10.1111/aogs.13828

  2. Chayachinda C, Baukaew L, Bangpichet A, Sodsee S, Pharkjaksu S. Clue Cell as a Single Diagnostic Tool for Bacterial Vaginosis during Pregnancy. J Med Assoc Thai [Internet]. 2020 [cited May 1st, 2022];103(4):353-8. Available from: http://www.jmatonline.com/index.php/jmat/article/view/11124

  3. Joyisa N, Moodley D, Nkosi T, Talakgale R, Sebitloane M, Naidoo M et al. Asymptomatic Bacterial Vaginosis in Pregnancy and Missed Opportunities for Treatment: A Cross-Sectional Observational Study. Infectious Diseases in Obstetrics and Gynecology [Internet]. 2019 [cited Apr 30, 2022];2019:1-7. Doi: https://doi.org/10.1155/2019/7808179

  4. Muzny C, Schwebke J. Asymptomatic Bacterial Vaginosis: to Treat or Not to Treat?. Current Infectious Disease Reports [Internet]. 2020 [cited May 1st, 2022];22(12). Doi: https://doi.org/10.1007/s11908-020-00740-z

  5. Kaambo E, Africa C, Chambuso R, Passmore J. Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis. Frontiers in Public Health [Internet]. 2018 [cited May 1st, 2022];6. Doi: https://doi.org/10.3389/fpubh.2018.00078

  6. Reiter S, Kellogg Spadt S. Bacterial vaginosis: a primer for clinicians. Postgraduate Medicine [Internet]. 2018;131(1):8-18. Doi: https://doi.org/10.1080/00325481.2019.1546534

  7. Foessleitner P, Kiss H, Deinsberger J, Ott J, Zierhut L, Rosta K et al. Screening Pregnant Women for Bacterial Vaginosis Using a Point-of-Care Test: A Prospective Validation Study. Journal of Clinical Medicine [Internet]. 2021;10(11):2275. Doi: https://dx.doi.org/10.3390/jcm10112275

  8. Jayaram P, Mohan M, Konje J. Bacterial vaginosis in pregnancy – a storm in the cup of tea. European Journal of Obstetrics & Gynecology and Reproductive Biology [Internet]. 2020;253:220-224. Doi: https://doi.org/10.1016/j.ejogrb.2020.08.009

  9. US Preventive Services Task Force. Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery US Preventive Services Task Force Recommendation Statement. JAMA [Internet]. 2020 [citado 1 May 2022];323(13):1286-1292. Doi: https://doi.org/10.1001/jama.2020.2684

  10. Javed A. Prevalence of Bacterial Vaginosis During Pregnancy in Tertiary Care Hospital, Lahore. Proceedings of Shaikh Zayed Medical Complex Lahore [Internet]. 2021;35(3):50-53. Doi: https://doi.org/10.47489/PSZMC-808-35-3-50-53

  11. Rebouças K, Jr. J, Peixoto R, Costa A, Cobucci R, Gonçalves A. Treatment of bacterial vaginosis before 28 weeks of pregnancy to reduce the incidence of preterm labor. International Journal of Gynecology & Obstetrics [Internet]. 2019;146(3):271-276. Doi: http://dx.doi.org/10.1002/ijgo.12829

  12. Basavaprabhu H, Sonu K, Prabha R. Mechanistic insights into the action of probiotics against bacterial vaginosis and its mediated preterm birth: An overview. Microbial Pathogenesis [Internet]. 2020;141:104029. Doi: https://doi.org/10.1016/j.micpath.2020.104029

  13. Powell A, Shary J, Louden C, Ramakrishnan V, Eckard A, Wagner C. Association of Bacterial Vaginosis with Vitamin D in Pregnancy: Secondary Analysis from the Kellogg Pregnancy Study. American Journal of Perinatology Reports [Internet]. 2019;09(03):e226-e234. Doi: https://doi.org/10.1055/s-0039-1693163

  14. Kahwati L, Clark R, Berkman N, Urrutia R, Patel S, Zeng J et al. Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to PreventPreterm Delivery. JAMA [Internet]. 2020;323(13):1293. Doi: https://doi.org/10.1001/jama.2020.0233

  15. Jin J. Screening for Bacterial Vaginosis During Pregnancy. JAMA [Internet]. 2020;323(13):1324. Available from: http://jamanetwork.com/article.aspx?doi=10.1001/jama.2020.2684

  16. Subtil D, Brabant G, Tilloy E, Devos P, Canis F, Fruchart A et al. Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial. The Lancet [Internet]. 2018;392(10160):2171-2179. Doi: https://doi.org/10.1016/S0140-6736(18)31617-9

  17. Miranda M, Saccone G, Ammendola A, Salzano E, Iannicelli M, De Rosa R et al. Vaginal lactoferrin in prevention of preterm birth in women with bacterial vaginosis. The Journal of Maternal-Fetal & Neonatal Medicine [Internet]. 2019;34(22):3704-3708. Doi: https://doi.org/10.1080/14767058.2019.1690445

  18. Hu C, Li F, Hua X, Jiang W, Zhang X. Longitudinal trajectory of vulvovaginal candidiasis, trichomoniasis, and bacterial vaginosis during pregnancy as well as the impact on pregnancy outcomes: a preliminary study. The Journal of Maternal-Fetal & Neonatal Medicine [Internet]. 2019;32(21):3612-3617. Doi: https://doi.org/10.1080/14767058.2018.1469125

  19. Shimaoka M, Yo Y, Doh K, Kotani Y, Suzuki A, Tsuji I et al. Association between preterm delivery and bacterial vaginosis with or without treatment. Scientific Reports [Internet]. 2019;9(1). Doi: https://doi.org/10.1038%2Fs41598-018-36964-2




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Revista Médica Sinergia. 2022;7