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Colegio de Medicina Interna de México.

2022, Number 4

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Med Int Mex 2022; 38 (4)

Adrenal insufficiency due to tuberculosis

González-Arnáiz E, González-Roza L, Ramos-Bachiller B, Ariadel-Cobo D, Ballesteros-Pomar MD

Language: Spanish
References: 12
Page: 948-952
PDF size: 205.38 Kb.


ABSTRACT

Background: Adrenal insufficiency is a generally progressive, insidious, hypofunctional disorder of the adrenal cortex. For many years, tuberculosis has been considered the leading cause of infectious adrenal insufficiency. Currently, the most frequent cause is autoimmune. Due to the non-specific symptoms of adrenal insufficiency and the low incidence of tuberculosis in non-endemic countries, the diagnosis and therefore treatment are delayed.
Clinical case: A 58-year-old male patient, diagnosed with pneumonia and a parapneumonic effusion of tuberculosis, with clinical and analytical data of adrenal insufficiency.
Conclusions: In non-endemic countries, extrapulmonary tuberculosis should be considered a possible cause of adrenal insufficiency. There may be an interaction between tuberculostatic drugs and corticosteroid treatment required in adrenal insufficiency. In most cases of tuberculosis-related adrenal insufficiency, adrenal function does not recover.


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