Alexander-Rodríguez J, Sánchez-Montoya MI, Oliveros-Riveros LM, Vásquez-Trespalacios EM

Language: Spanish
References: 19
Page: 777-785
PDF size: 211.75 Kb.

ABSTRACT

Introduction: Cervical cancer remains a prevalent entity, however, primary cervical adenocarcinoma with signet ring cells is a rare condition categorized as one of the subtypes of mucinous adenocarcinomas with fewer scientific reports. This can debut with a wide variety of gynecological and gastrointestinal symptoms that require exhaustive studies to identify the primary focus, therefore this report demonstrates how one of its presentations can be primary of the cervix without presenting gastrointestinal involvement in a patient previously healthy with no risk factors.
Clinical case: A 31-year-old patient with no pathological history diagnosed with an invasive signet ring cell adenocarcinoma who debuted with postcoital bleeding, a cytology that reported a low-grade intraepithelial lesion (LIEB) and colposcopy with positive immunohistochemistry for CK7, CK20, CA125 , CEA, P16, KI67. Complementary studies were performed, metastatic lesions were ruled out, classifying it as stage IB2, a radical hysterectomy, pelvic lymphadenectomy was carried out, after chemotherapy with cisplatin and pelvic radiotherapy. At the date of the last follow-up, the patient is stable, in controls and free of the disease.
Conclusion: Primary signet ring cell adenocarcinoma of the cervix is a rare entity, with a difficult diagnosis, in which the existence of a non-gynecological primary tumor must be ruled out, and once the primary tumor in the cervix is confirmed, provide the treatment.

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