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2021, Number 3

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Rev Cuba Enf 2021; 37 (3)

Scientific evidence regarding the applicability of ascorbic acid against skin lesions

de Souza NVL, de Oliveira MEC, Santos VB, de Lima LJ

Language: Spanish
References: 16
Page: 1-15
PDF size: 624.48 Kb.


ABSTRACT

Introduction: Skin lesions are characterized by break in the continuity of tissue resulting from several factors. Therefore, the medical care provided to people with skin lesions must be multidimensional and interdisciplinary. One of the therapeutic alternatives that is increasingly being used for the treatment of patients with skin lesions is the use of natural products, such as ascorbic acid.
Objective: To analyze the best scientific evidence on the use of ascorbic acid as a therapeutic method against skin lesions.
Methods: Systematic review consisting in search for studies in the databases Pubmed, Scopus, Cinahl, Web of Science and The Cochrane Data Base, with research directed to the applicability of ascorbic acid against skin lesions. The studies were paired and ranked according to their best scientific evidence.
Conclusion: After analyzing the clinical trials, which presented scientific solidity, it was noted that there is some promotion of the contribution of ascorbic acid to healing, since it decreases the inflammatory process and leads to neovascularization, to concentration of macrophages, as well as of fibroblasts and collagen fibers. Among the studies analyzed, it is evidenced that the use of ascorbic acid has an effect on the therapeutic process of patients with injuries, but new studies are required to complement this thesis.


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