Martínez-Camacho H, Morfín L, Brito A, Cruz B

Language: Spanish
References: 6
Page: 1132-1135
PDF size: 193.59 Kb.

ABSTRACT

Background: In the framework of the COVID-19 pandemic, some miracle products have emerged as part of the disease therapy, one of them has been chlorine dioxide and its derivatives. The Pan American Health Organization (PAHO), the European Medicines Agency (AEM) and the US Food and Drug Administration (FDA) have prepared and issued statements warning about the lack of scientific evidence in relation to its efficacy in disease caused by SARS-CoV-2 and on risks to human health.
Clinical case: A 62-year-old female, with a previous history of jaundice not studied. She presented a 3-week evolution with mesogastric colic pain and generalized jaundice, associated with the ingestion of chlorine dioxide during the 3 previous months. Liver function tests: TGO: 2316 U/L, TGP: 1449 U/L, FA: 531.2 U/L, BBT: 10.41 mg/dL, BBD: 7.14 mg/dL, BBI: 3.27 mg/dL; liver ultrasound reported degenerative liver disease. Liver biopsy was compatible with toxic “drug” hepatitis.
Conclusions: Chlorine dioxide belongs to a list of products that have been promoted without scientific support as prophylactic or therapeutic agents for the management of SARS-CoV-2 disease; however, the absence of evidence on its usefulness and the development of adverse effects, such as liver toxicity, have been documented in this and other publications; thus, it is recommended to avoid its administration.

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