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2022, Number 5

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Acta Pediatr Mex 2022; 43 (5)

Association between pediatric Guillain-Barré syndrome and COVID-19: case report

Manzanera-Ornelas DA, Aguirre-García MI, Romero-Jacobo GM, Quintero-Jurado GL, Saad-Manzanera MI, Guerrero-Lara MF

Language: Spanish
References: 12
Page: 280-286
PDF size: 357.76 Kb.


ABSTRACT

Background: On March 11, 2020, SARS-CoV-2 infection was declared a pandemic, establishing mainly respiratory and gastrointestinal symptoms. The infection in pediatric patients has had an important variety of symptoms, highlighting neurological alterations. There has been an increase in reports of Guillain-Barré Syndrome, however, these are rare.
Clinical case: 10-year-old male, who starts with lower limbs weakness, productive cough, and fever; with a history of hospitalization at age of 2-years-old for Guillain- Barré Syndrome for 15 days, with complete recovery. Once in our unit, chest Computed Tomography was performed with suggestive data of COVID-19, RT-PCR was requested for SARS-Cov-2 with positive result, in addition to an electromyography where results were consistent with a demyelinating polyneuropathy compatible with variant of acute motor axonal neuropathy in all extremities. Despite the management with gammaglobulin and plasmapheresis, the patient did not have an adequate evolution and died.
Conclusion: The diagnosis and treatment of Guillain-Barré Syndrome related to COVID-19 in pediatric patients has been shown to be a real challenge as there are few reports in the literature, so the importance of this case review is to keep in mind the diversity of manifestations that are presented in COVID-19 infection and contemplate it in the differential diagnosis of encephalitis and infectious conditions with neurological manifestations.


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