medigraphic.com
Federación Mexicana de Ginecología y Obstetricia, A.C.

2022, Number 12

<< Back Next >>

Ginecol Obstet Mex 2022; 90 (12)

Phyllodes tumor: A 12-year experience at Oncology Unit of the Hospital General de Puebla

Pinedo-Vega ÁD, Orea-Estudillo D, Hernández-Bernal PA, Pérez-Soriano A, Sánchez-Vázquez B, Pinedo-Vega ME

Language: Spanish
References: 20
Page: 951-958
PDF size: 186.56 Kb.


ABSTRACT

Objective: To present the 12-year experience of the Oncology Unit of the General Hospital of Puebla Eduardo Vázquez N in the treatment of patients with phyllodes tumor.
Materials and Methods: Longitudinal, restrospective, observational and clinical study carried out in patients with histopathological diagnosis of phyllodes tumor attended from January 2009 to December 2021 in the Oncology Unit of the General Hospital of Puebla. Study variables: incidence, age at diagnosis, location and surgical technique applied. Parametric measures were applied to determine the variables between independent groups.
Results: Thirty-seven files of patients with a diagnosis of phyllodes tumor were reviewed. An institutional incidence of 1.4% was obtained, of which 18.9% corresponded to malignant tumor. The mean age of the patients was 39.4 (limits 13 to 61 years). In two cases an association with pregnancy was found. In general terms, treatment was surgical, with simple mastectomy and lumpectomy, with recurrence in six cases.
Conclusions: Although the incidence of phyllodes tumor is low, it is always important to consider its existence as an alternative for the diagnosis of breast tumors. Surgical treatment with simple mastectomy has seemed to have a good response, with low recurrence rates.


REFERENCES

  1. Stamatakos M, Tsaknaki S, Kontzoglou K, Gogas J, KostakisA, Safioleas M. Phylloides tumor of the breast: A rareneoplasm, though not that innocent. Int Semin Surg Oncol 2009; 6: 4-7. doi:10.1186/1477-7800-6-6

  2. Hopkins ML, McGowan TS, Rawlings G, Liu F ‐F, Fyles AW,Yeoh JL, et al. Phylloides tumor of the breast: A report of 14cases. J Surg Oncol 1994; 56 (2): 108-12. doi:10.5144/0256-4947.2013.162

  3. Rayzah M. Phyllodes tumors of the breast: a literaturereview. Cureus 2020; 12 (9). doi:10.7759/cureus.10288

  4. Aranda C, Sotelo M, Torres A, Zárate M. Tumor phyllodes yembarazo. Reporte de un caso. Ginecol Obstet Mex 2005;73 (7): 387-92.

  5. Tse GMK, Niu Y, Shi HJ. Phyllodes tumor of the breast: Anupdate. Breast Cancer 2010; 17 (1): 29-34. doi:10.1007/s12282-009-0114-z

  6. Ercilla Orbañanos J, Martí Sopeña M, Martínez Gómez E,González de Diego MH, Arnanz Velasco F, Zapico Goñi A.Phyllodes breast tumour: experience over 11 years andliterature review. Clin Invest Ginecol Obstet 2021; 48 (2):196-200. https://doi.org/10.1016/j.gine.2020.11.006

  7. Al-Zoubaidi M, Qiu S, Bonnen M, Joyner M, Roehl K,Silva C, et al. Malignant phyllodes tumor of the breast:A case report. Open Breast Cancer J 2011; 3 (C): 45-488.doi:10.2174/1876817201103010045

  8. Kraemer B, Hoffmann J, Roehm C, Gall C, Wallwiener D,Krainick-Strobel U. Cystosarcoma phyllodes of the breast:A rare diagnosis: Case studies and review of literature.Arch Gynecol Obstet 2007; 276 (6): 649-53. doi: 10.1007/s00404-007-0393-6

  9. Zhang Y, Kleer CG. Phyllodes tumor of the breast histopathologicfeatures, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med 2016; 140 (7): 665-71. doi:10.5858/arpa.2016-0042-RA

  10. Papas Y, Asmar A El, Ghandour F, Hajj I. Malignant phyllodestumors of the breast: A comprehensive literature review.Breast J 2020; 26 (2): 240-4. doi:10.1111/tbj.13523

  11. Wang Q, Su J, Lei Y. Recurrent malignant phyllodes tumorof the breast. Med (United States) 2017; 96 (49): 10-2.doi:10.1097/MD.0000000000009069

  12. Spitaleri G, Toesca A, Botteri E, Bottiglieri L, Rotmensz N,Boselli S, et al. Breast phyllodes tumor: A review of literatureand a single center retrospective series analysis. CritRev Oncol Hematol 2013; 88 (2): 427-36. http://dx.doi.org/10.1016/j.critrevonc.2013.06.005

  13. Boland PA, Ali Beegan A, Stokes M, Kell MR, Barry JM,O’Brien A, et al. Management and outcomes of phyllodestumours - 10 year experience. Breast Dis 2021; 40 (3):171-6. doi:10.3233/BD-201059

  14. Carlson RW, Wilbur Drive B, LTelli M, Horst KC, Guardino AE,Dirbas FM. From the departments of medicine, radiationoncology, and phyllodes tumors of the breast: naturalhistory, diagnosis, and treatment historical overview. JNatl Compr Cancer Netw 2007; 5 (3): 324-30. doi:10.6004/jnccn.2007.0027

  15. Korpanty G, Power DG. Phyllodes tumor of the breast. MedOncol 2011; 28 (Suppl 1): S62-42011;62-4. doi:10.1007/s12032-010-9695-9

  16. Graña López L, Vázquez Caruncho M, Villares Armas Á.Percutaneous removal of benign phyllodes tumor of thebreast: An alternative to surgery. Breast J 2018; 24 (6):1035-7. doi:10.1111/tbj.13122

  17. Brenes JM, Furió V, Moreno MA, Merchán MJ, Ruiz J,Olivares ME, et al. Clinical management, treatment andlocal control of phyllodes tumors. Rev Senol y PatolMamar 2013; 26 (2): 52-7. http://dx.doi.org/10.1016/j.senol.2013.02.003

  18. Rockbrand Campos LP, Koutsowris Sáenz S, GarcíaCarranza MA, Castro González M, Sibaja MatamorrosDA. Tumor Phyllodes: revision de la literaturaTT - Phyllodes tumor: literature review. Med leg CostaRica 2020; 37 (1): 146-53. http://www.scielo.sa.cr/scielo.php?script=sci_arttext&%0Apid=S1409-00152020000100146%0Ahttps://fi-admin.bvsalud.org/document/view/cavbh

  19. Ogunbiyi S, Perry A, Jakate K, Simpson J, George R. Phyllodestumour of the breast and margins: How much isenough? Can J Surg 2019; 62 (1): E19-21. doi:10.1503/cjs.005718

  20. Rayzah M. Phyllodes Tumors of the breast: a literaturereview. Cureus. 2020; 12 (9): e10288. doi: 10.7759/cureus.10288




2020     |     www.medigraphic.com