Alcántar-Arenas MM, Gutiérrez-Ávila S, Alcántara-Ramírez V, Hierro-Orozco S, Salamanca-García M, Rodríguez RA

Language: Spanish
References: 5
Page: 412-414
PDF size: 158.83 Kb.

ABSTRACT

Rosai-Dorfman disease is a disorder that belongs to the histiocytosis group; 90% of patients have lymphadenopathy with systemic involvement, and 10% are exclusively cutaneous. The classic presentation of this disease, its a cutaneous form, an infiltrated and asymptomatic erythematous plaque with the presence of surrounding papules. On histopathology, it is characteristic to find emperipolesis, as well as positivity for s100 and CD68. Patients with skin involvement can receive steroid, thalidomide, methotrexate, and surgical removal as treatment options, with variable results. This pathology usually has a benign course and a favorable prognosis. We present a 31-yearold case with a history of Marfan syndrome, who was evaluated for presenting asymptomatic papular neoformations of three months of evolution.

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