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2023, Number 2

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Acta Med 2023; 21 (2)

Use of near-infrared spectroscopy in monitoring for the prevention of brain damage in preterm infants. Systematic review of the literature

Yepez GPA, Núñez PAJ, Orozco GA
Full text How to cite this article 10.35366/110262

DOI

DOI: 10.35366/110262
URL: https://dx.doi.org/10.35366/110262

Language: Spanish
References: 11
Page: 151-157
PDF size: 173.17 Kb.


Key words:

near-infrared spectroscopy, neonatal monitoring, preterm neonates, prevention of brain injury.

ABSTRACT

Near-infrared spectroscopy (NIRS) is a non-invasive optical diagnostic method as a guide to taking corrective measures to prevent brain injury in premature infants. This review aims to evaluate the efficacy of NIRS in detecting cerebral oxygenation and its impact on preventing brain injury and mortality in preterm. A systematic search of the literature was carried out in PubMed and Cochrane with the keywords spectroscopy, near-infrared, preterm newborn, infant, neonates, Clinical Trial, Meta-Analysis, and systematic to find studies that evaluate the use of the NIRS in cerebral oxygenation in preterm newborns. A phase II clinical trial, a phase III clinical trial, and a systematic review were included. NIRS significantly reduced the burden of cerebral hypoxia. The NIRS showed trends in reducing mortality and brain injury but did not show a statistically significant difference.


REFERENCES

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  2. United Nations Department of Economic and Social Affairs. Millennium development goals report 2015. United Nations. 2016.

  3. Liu L, Oza S, Hogan D, Chu Y, Perin J, Zhu J et al. Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet. 2016; 388 (10063): 3027-3035.

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  5. Kooi EMW, Verhagen EA, Elting JWJ, Czosnyka M, Austin T, Wong FY et al. Measuring cerebrovascular autoregulation in preterm infants using near-infrared spectroscopy: an overview of the literature. Expert Rev Neurother. 2017; 17 (8): 801-818.

  6. Pansy J, Baik N, Schwaberger B, Scheuchenegger A, Pichler-Stachl E, Avian A et al. Cerebral hypoxia during immediate transition after birth and short term neurological outcome. Early Hum Dev. 2017; 110: 13-15.

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  8. Hyttel-Sorensen S, Pellicer A, Alderliesten T, Austin T, van Bel F, Benders M et al. Cerebral near infrared spectroscopy oximetry in extremely preterm infants: phase II randomised clinical trial. BMJ. 2015; 350: g7635.

  9. Pichler G, Urlesberger B, Baik N, Schwaberger B, Binder-Heschl C, Avian A et al. Cerebral oxygen saturation to guide oxygen delivery in preterm neonates for the immediate transition after birth: a 2-center randomized controlled pilot feasibility trial. J Pediatr. 2016; 170: 73-8.e1-4.

  10. Hyttel-Sorensen S, Greisen G, Als-Nielsen B, Gluud C. Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants. Cochrane Database Syst Rev. 2017; 9 (9): CD011506.

  11. Hyttel-Sorensen S, Austin T, van Bel F, Benders M, Claris O, Dempsey E et al. A phase II randomized clinical trial on cerebral near-infrared spectroscopy plus a treatment guideline versus treatment as usual for extremely preterm infants during the first three days of life (SafeBoosC): study protocol for a randomized controlled trial. Trials. 2013; 14: 120.




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Acta Med. 2023;21