medigraphic.com
SPANISH

Archivos de Cardiología de México

  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2003, Number s1

<< Back Next >>

Arch Cardiol Mex 2003; 73 (s1)

Challenges and opportunities in the control of ventricular arrhythmias

González HGJA
Full text How to cite this article

Language: Spanish
References: 10
Page: 48-52
PDF size: 57.96 Kb.


Key words:

Sudden death, Anatomic nervous system, Heart rate variability.

ABSTRACT

Sudden cardiac death continues to be a significant health care problem. Patients with prior myocardial infarction, severe left ventricular dysfunction, and nonsustained ventricular tachycardia are at high risk for sudden death.
Identification of patients prone to sudden cardiac death is still unresolved, although a number of strategies have been applied over the past two decades based on the degree of left ventricular dysfunction, frequency of spontaneous ventricular arrhythmias, and ventricular late potentials. It has been recognized that patients with myocardial infarction and depressed left ventricular function have enhanced sympathetic relative to vagal tone controlling cardiac rhythm and rate. This can be measured as depressed heart rate variability and baroreflex sensitivity. Other markers of risk have been explored, QT dispersion, post-extrasystolic heart rate turbulence and T wave alternans.
Development of the automatic ICD has been one of the most spectacular achievements of the last 20 years in cardiology. The ICD reduces sudden death in postmyocardial infarction patients. Nevertheless, a clearer delineation is needed of the subsets of patients in whom an optimal medical regimen migth be the best option for preventing sudden death.


REFERENCES

  1. Castellanos A, Myerburg RJ: Cardiac arrest and sudden cardiac death. En: Braunwald E, ed. Heart disease: a textbook of cardiovascular medicine. New York: WB Saunders Publishing Co 2001: 890-931.

  2. Myerburg RJ, Kessler KM, Castellanos A: Pathophysiology of sudden cardiac death. PACE 1991; 14: 935-943.

  3. Zipes DP, Wellens HJJ: Sudden cardiac death. Circulation 1998; 98: 2334-2351.

  4. Hermosillo AG, Araya V, Casanova JM: Risk stratification for malignant arrhythmic events in patients with an acute myocardial infarction: role of an open infarct-related artery and the signal averaged ECG. Coronary Artery Dis 1995; 6: 973-983.

  5. Schwartz PJ, Zipes DP: Autonomic modulation of cardiac arrhythmias. En: Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. Philadelphia, Pa: WB Saunders Co 2000: 300-314.

  6. Hermosillo AG, Dorado M, Casanova JM, Ponce de Leon S, Cossio J, Kersenovich S, et al: Influence of infarct-related artery patency on the indexes of parasympathetic activity and prevalence of late potentials in survivors of acute myocardial infarction. J Am Coll Cardiol 1993; 22: 695-706.

  7. La Rovere MT, Bigger JT Jr, Marcus FI Mortana A, Schwartz PJ: Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. Lancet 1998; 351: 478-484 .

  8. La Rovere MT, Pinna GD, Hohnloser SH, Marcus FI, Mortana A, Nohara R, et al: On behalf of the ATRAMI Investigators. Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials. Circulation 2001; 103: 2072-2077.

  9. La Rovere MT, Bersano Ch, Gnemmi M, Specchia G, Schwartz PJ: Exercise-induced increase in baroreflex sensitivity predicts improved prognosis after myocardial infarction. Circulation 2002; 106: 945-949.

  10. Böcker D, Breithardt G: Evaluating AVD, CASH, CIDS, CABG-Patch and MADIT: Are they concordant? J Interven Cardiac Electrophysiol 2000; 4: 103-108.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Arch Cardiol Mex. 2003;73