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2023, Number 1

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Rev Mex Pediatr 2023; 90 (1)

Ultra-short bowel syndrome and metabolic bone disease in a patient on total parenteral nutrition

Anaya-Flórez MS, Barbosa-Cortés ML, Barraza TA
Full text How to cite this article 10.35366/112595

DOI

DOI: 10.35366/112595
URL: https://dx.doi.org/10.35366/112595

Language: Spanish
References: 13
Page: 22-26
PDF size: 278.69 Kb.


Key words:

ultra-short bowel syndrome, total parenteral nutrition, metabolic bone disease, 25-hydroxyvitamin D.

ABSTRACT

Introduction: pediatric short bowel syndrome (SBS) patients receiving prolonged total parenteral nutrition (TPN) may develop bone mineral disease by different mechanisms. Case report:16-year-old female adolescent who has received TPN support for more than a year, after resection of both an abdominal tumor and a large portion of intestine, for which the residual intestine was 5 cm of jejunum, without valve ileocecal or ascending colon and half of transverse colon. Six months after TPN, she presented vitamin D deficiency (12.9 ng/mL), so the dose was increased to 400 IU in TPN. After five months, vitamin D values remained low (21.9 ng/dL), for which cholecalciferol was added, reaching normal levels. During this period, it was found that bone mineral density was low, but it improved with vitamin D supplementation. Conclusions: the data from this clinical case indicate the need to monitoring of bone health in patients with SBS dependent on prolonged TPN.


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C?MO CITAR (Vancouver)

Rev Mex Pediatr. 2023;90