Del CMA, Trujillo-Sánchez AU, Del CAP, Lara-López A, Rosas-Trujillo LB, García-Castañeda FA, Medina-Pérez M, Campante-Arteaga AA, Agredano-Espinoza JD, Curiel-Vargas DM, Santillán-Sánchez LG

Language: Spanish
References: 11
Page: 32-36
PDF size: 186.77 Kb.

ABSTRACT

Granulomatosis with polyangiitis is a rare and serious autoimmune condition. In addition to typical symptoms, some patients may present invasion of the central nervous system, manifested as central diabetes insipidus. However, this complication occurs in less than 1%, making it a diagnostic challenge. We report the case of a 33-year-old patient previously diagnosed with granulomatosis with polyangiitis following a bout of alveolar hemorrhage, who started treatment with azathioprine and prednisone. Upon tapering off prednisone, she developed temporal headache, polyuria, and polydipsia. We present the diagnostic approach of a patient with the main clinical feature of polyuria. The presentation of cases with atypical progression is essential to improve understanding and management of this rare but significant condition in the context of granulomatosis with polyangiitis.

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