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Colegio de Medicina Interna de México.

2024, Number 03

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Med Int Mex 2024; 40 (03)

Post-COVID-19 syndrome associated with cerebral vasoreactivity

Sotelo NC, Dávila SD, Suárez CJA, García LVH

Language: Spanish
References: 19
Page: 179-190
PDF size: 241.58 Kb.


ABSTRACT

Objective: To evaluate the effect of SARS-CoV-2 infection on changes in cerebral vasoreactivity in patients meeting the criteria for post-COVID-19 syndrome.
Materials and Methods: A case-control, analytical, cross-sectional, descriptive, retrospective, observational study, in which information were collected from digital clinical file of patients with history of having entered to the Internal Medicine of General Hospital Tlahuac from September to December 2020, with COVID-19-positive test by PCR. Cerebral vasoreactivity was measured using transcranial Doppler ultrasonography, with a temporal window approach, without lateral predominance, to record baseline and 10-second post-30-second voluntary apnea flow velocities in the middle cerebral artery. This assessment was conducted on patients meeting the definition of post- COVID-19 syndrome, while control measurements were taken on medical residents and healthcare workers with a history of SARS-CoV-2 infection.
Results: Sixty-two patients with an average age of 42 years were studied. They were divided into two groups. Group 1 with 20 patients with post-COVID-19 syndrome and group 2 with 42 patients without the syndrome. Lower systolic and diastolic velocities were observed in the post-COVID-19 syndrome group, both at baseline and post-apnea. Additionally, reduced systolic and diastolic vasoreactivity in patients with post-COVID-19 syndrome was found.
Conclusions: Post-COVID-19 syndrome was associated with decreased cerebral vasoreactivity, independent of sex, age, and comorbidities.


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