Fernández GAS, Morales CGM

Language: Spanish
References: 10
Page: 74-82
PDF size: 184.57 Kb.

ABSTRACT

Objective: To compare the cytological diagnosis of fine needle aspiration biopsies and the ultrasonographic finding of thyroid nodules with the definitive post-thyroidectomy histopathological diagnosis in patients from the Hospital Español de Mexico.
Materials and Methods: An observational, cross-sectional, descriptive, retrolective study, which reviewed patients’ records at the Hospital Español de Mexico with thyroid nodules who underwent fine-needle aspiration biopsy and/or ultrasonographic study prior to thyroidectomy in 2019 and 2020. Results of the aforementioned presurgical studies were compared to the definitive post-thyroidectomy histopathological result.
Results: Three study groups were formed: 23 patients who underwent fine needle aspiration biopsy and thyroidectomy, 37 patients who had an ultrasound study prior to performing thyroidectomy, but no fine needle aspiration biopsy was performed, and 25 patients who had fine needle aspiration biopsie and ultrasound prior to surgical procedure. All patients with a Bethesda classification I, II and III had a benign post-thyroidectomy report. Of the Bethesda IV classification, 28.5% were reported as malignant. All patients with TI-RADS 1, 2 and 3 had a benign post-thyroidectomy report. Of the TI-RADS 4 classification, 23% were reported as malignant, 100% of TI-RADS 5 had a post-thyroidectomy report of benignity, there were no reports of TI-RADS 6.
Conclusiones: The higher the Bethesda classification, the greater the risk of having a definitive malignancy result. No relationship was found between the results of the TI-RADS ultrasonographic classification with the definitive post-thyroidectomy histopathological result.

REFERENCES

1. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines forAdult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid AssociationGuidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid 2016; 26 (1): 1-133.doi:10.1089/thy.2015.0020

2. Antonia TD, Maria LI, Ancuta-Augustina GG. Preoperative evaluation of thyroid nodules - Diagnosis andmanagement strategies. Pathol Res Pract 2023; 246: 154516. doi: 10.1016/j.prp.2023.154516

3. Yeh MW, Bauer AJ, Bernet VA, Ferris RL, et al; American Thyroid Association Surgical Affairs CommitteeWriting Task Force. American Thyroid Association statement on preoperative imaging for thyroid cancersurgery. Thyroid 2015; 25 (1): 3-14. doi: 10.1089/thy.2014.0096

4. Nie W, Zhu L, Yan P, Sun J. Thyroid nodule ultrasound accuracy in predicting thyroid malignancy based onTIRADS system. Adv Clin Exp Med 2022; 31 (6): 597-606. doi: 10.17219/acem/146776

5. Jat MA. Comparison of surgeon-performed ultrasound-guided fine needle aspiration cytology with histopathologicaldiagnosis of thyroid nodules. Pak J Med Sci 2019; 35 (4): 1003-1007. doi: 10.12669/pjms.35.4.537

6. Li F, Pan D, Wu Y, Peng J, et al. Ultrasound characteristics of thyroid nodules facilitate interpretation of themalignant risk of Bethesda system III/IV thyroid nodules and inform therapeutic schedule. Diagn Cytopathol2019; 47 (9): 881-889. doi: 10.1002/dc.24248

7. Cibas ES, Ali SZ. The Bethesda System for Reporting Thyroid Cytopathology. Thyroid 2009; 19 (11): 1159-65. doi: 10.1089/thy.2009.0274

8. Jamaiyar A, Yogesh K. How accurate is fine-needle aspiration cytology (FNAC) for thyroid lesion: A correlationof FNAC with histopathology. J Family Med Prim Care 2023; 12 (1): 15-20. doi: 10.4103/jfmpc.jfmpc_1413_21

9. Tang AL, Falciglia M, Yang H, Mark JR, Steward DL. Validation of American Thyroid Association ultrasoundrisk assessment of thyroid nodules selected for ultrasound fine-needle aspiration. Thyroid 2017; 27(8): 1077-1082. doi: 10.1089/thy.2016.0555

10. Espinosa De Ycaza AE, Lowe KM, Dean DS, Castro MR, et al. Risk of malignancy in thyroid nodules withnon-diagnostic fine-needle aspiration: A retrospective cohort study. Thyroid 2016; 26 (11): 1598-1604. doi:10.1089/thy.2016.0096