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2024, Number 4

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Acta Med 2024; 22 (4)

Pharmacological treatment in diabetic neuropathy. Fantasy or reality?

Díaz GEJ, Sánchez AR, Santibañez SV
Full text How to cite this article 10.35366/117518

DOI

DOI: 10.35366/117518
URL: https://dx.doi.org/10.35366/117518

Language: Spanish
References: 15
Page: 290-295
PDF size: 264.28 Kb.


Key words:

diabetes, hyperglycemia, chronic pain.

ABSTRACT

Diabetic neuropathy is the most common neurological complication in patients with diabetes; it is estimated that 16% of people with diabetes present this condition. Of all neuropathies in diabetic patients, 75% fall under the category of "distal symmetric polyneuropathy" or DSPN; peripheral neuropathy can encompass any disorder of the peripheral nervous system, including radiculopathies and mononeuropathies. Among the clinical manifestations, one of the primary symptoms is pain, described as burning or stabbing, which can either improve or worsen, leading to walking difficulties. It is important to emphasize that prevention is the number one method for managing neuropathy, focusing on glucose control and lifestyle modifications. According to evidence, duloxetine is recommended as the first-line pharmacological treatment, followed by pregabalin as the second line, and tapentadol as the third line.


REFERENCES

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Acta Med. 2024;22