Morales MV, Sánchez PMJ, Rodríguez WFL

Language: Spanish
References: 15
Page: 302-306
PDF size: 252.20 Kb.

ABSTRACT

Autoimmune polyendocrine syndromes (APS) are a rare condition that includes a group of manifestations derived from the loss of immune tolerance in endocrine glands and can also affect non-endocrine organs. Currently, they can be divided into rare monogenic forms, such as autoimmune polyendocrine syndrome type 1 (APS1) and a more common polygenic variant, type 2 (APS2) or Schmidt syndrome. They occur in childhood or adulthood and are characterized by circulating autoantibodies and lymphocytic infiltration of tissues or organs that cause organ failure. The clinical manifestations are varied, and delays in diagnosis are common.

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