de la Rosa-Garibay E, Cano-Lizárraga IE, Ceballos-Pérez MP, Arenas R

Language: Spanish
References: 12
Page: 227-231
PDF size: 143.53 Kb.

ABSTRACT

Background: onychomycosis is a chronic fungal infection affecting fingernails and toenails, mainly caused by dermatophytes such as Trichophyton rubrum. It is the most common nail infection in clinical practice, characterized by discoloration, nail thickening, and onycholysis. Risk factors include immunosuppression, diabetes mellitus, and rheumatoid arthritis (RA).
Objectives: to describe the frequency of toenail onychomycosis in ra patients with clinical suspicion of onychomycosis and to analyze the epidemiological, clinical, and mycological features.
Methodology: a cross-sectional and retrospective study was conducted on ra patients at the Mycology Section, Dr. Manuel Gea González General Hospital with suspected onychomycosis from 2012 to 2022. Clinical and demographic, as well as koh-clorazol black examinations and cultures on Sabouraud agar data were collected.
Results: We studied 79 patients with ra and onychomycosis was confirmed in 69.6% (55 patients). We found female predominance (f:m; 5.9:1) with an age range of 28 to 88 years. Trichophyton rubrum was the most common isolated fungus (52.9%), followed by Candida spp. (29.4%). The most frequent clinical variant was total dystrophic onychomycosis (49.1%).
Conclusions: this study highlights that roughly two-third of ra patient had onychomycosis, mainly total dystrophic onychomycosis caused by Trichophyton rubrum.

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