medigraphic.com
ISSN 2007-3178 (Print)
Asociación Mexicana de Cirugía Bucal y Maxilofacial, Colegio Mexicano de Cirugía Bucal y Maxilofacial, A.C.

2024, Number 2

<< Back Next >>

Rev Mex Cir Bucal Maxilofac 2024; 20 (2)

Primordial odontogenic tumor, a complex entity of development: literature review

Aguayo CRA

Language: Spanish
References: 26
Page: 55-61
PDF size: 381.61 Kb.


ABSTRACT

Introduction: the primordial odontogenic tumor (POT) is a rare odontogenic tumor. The World Health Organization (WHO) in 2017 and 2022 classified it as a benign, mixed neoplasm. To date, only 23 cases have been documented in the world. Objectives: to analyze clinical and radiographic histopathological characteristics and treatment reported to date. Material and methods: an exhaustive electronic search was carried out in august and September of the year 2022, with date restrictions from 2014 where the TOP was reported for the first time. PubMed and ScienceDirect databases were accessed. Results: a total of 16 publications were included, representing 23 reported cases of TOP. Conclusions: TOP is a benign mixed odontogenic neoplasm, with prevalence in the first two decades of life, it presents clinically as an increase in volume, mainly mandibular and asymptomatic. Radiographically, a unilocular or multilocular lesion associated with an unerupted tooth is observed. Due to its low prevalence, it is essential to carry out a complete clinical, radiographic and histopathological study for the definitive diagnosis of this pathology. The treatment of choice is enucleation and extraction of the affected tooth. Larger studies with long-term follow-up are needed to create a strict treatment protocol, since few cases have been reported to date.


REFERENCES

  1. El-Naggar AK, Chan J, Takata T et al. WHO classification of head and neck tumours. 4th edition. Vol. 9. Lyon: IARC; 2017.

  2. Vered M, Wright JM. Update from the 5th edition of the World Health Organization classification of head and neck tumors: odontogenic and maxillofacial bone tumours. Head Neck Pathol. 2022; 16 (1): 63-75. doi: 10.1007/s12105-021-01404-7.

  3. Mosqueda-Taylor A, Pires FR, Aguirre-Urízar JM, Carlos-Bregni R, de la Piedra-Garza JM, Martínez-Conde R et al. Primordial odontogenic tumour: clinicopathological analysis of six cases of a previously undescribed entity. Histopathology. 2014; 65 (5): 606-612. doi: 10.1111/his.12451.

  4. Slater LJ, Eftimie LF, Herford AS. Primordial odontogenic tumor: report of a case. J Oral Maxillofac Surg. 2016; 74 (3): 547-551. doi: 10.1016/j.joms.2015.08.019.

  5. Ando T, Shrestha M, Nakamoto T, Uchisako K, Yamasaki S, Koizumi K et al. A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017). Pathol Int. 2017; 67 (7): 365-369. doi: 10.1111/pin.12543.

  6. Mikami T, Ohashi Y, Bologna-Molina R, Mosqueda-Taylor A, Fujiwara N, Tsunoda N et al. Primordial odontogenic tumor: a case report with histopathological analyses. Pathol Int. 2017; 67 (12): 638-643. doi: 10.1111/pin.12601.

  7. Pardhe N, Bajpai M. Primordial odontogenic tumor of mandible; a case with proposed diagnostic criteria. Iran J Med Sci. 2018; 43 (1): 97-99.

  8. Almazyad A, Li CC, Tapia ROC, Robertson JP, Collette D, Woo SB. Primordial odontogenic tumour: report of two cases. Histopathology. 2018; 72 (7): 1221-1227. doi: 10.1111/his.13488.

  9. Amer H, Hafed L, Ibrahim S. Case report: a primordial odontogenic tumor. F1000Res. 2018; 7: 562. doi: 10.12688/f1000research.14735.1.

  10. Bomfim BB, Prado R, Sampaio RK, Conde DC, de Andrade BAB, Agostini M et al. Primordial odontogenic tumor: report of a new case and literature review. Head Neck Pathol. 2019; 13 (2): 125-130. doi: 10.1007/s12105-018-0913-7.

  11. Teixeira LN, Furuse C, Santos FP, Soares AB, de Oliveira EMF, de Araújo NS et al. The challenging diagnosis of primordial odontogenic tumor. Case Rep Dent. 2019; 2019: 6415785. doi: 10.1155/2019/6415785.

  12. Sun Q, Lee JS, Kim O, Kim Y. Primordial odontogenic tumor: a case report and literature review. Diagn Pathol. 2019; 14 (1): 92. doi: 10.1186/s13000-019-0867-4.

  13. Poomsawat S, Ngamsom S, Nonpassopon N. Primordial odontogenic tumor with prominent calcifications: a rare case report. J Clin Exp Dent. 2019; 11 (10): e952-e956. doi: 10.4317/jced.55925.

  14. Delgado-Azañero WA, de Almeida OP, Pereira AAC, de Oliveira CE, Dias MA et al. Primordial odontogenic tumor: report of 2 new cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021; 132 (2): e69-e77. doi: 10.1016/j.oooo.2020.08.004.

  15. Sato H, Chikuda J, Inada T, Shirota T. A peripheral primordial odontogenic tumor: unique case report. Oral Maxillofac Surg Cases. 2020; 6: 100163. doi: 10.1016/j.omsc.2020.100163.

  16. Kayamori K, Tsuchiya M, Michi Y, Kuribayashi A, Mikami T, Sakamoto K et al. Primordial odontogenic tumor occurred in the maxilla with unique calcifications and its crucial points for differential diagnosis. Pathol Int. 2021; 71 (1): 80-87. doi: 10.1111/pin.13036.

  17. Naina S, Narwal A, Devi A, Kamboj M, Pandiar D. Primordial odontogenic tumor of anterior maxilla in a young male: a case report and an updated review of literature. Pediatr Dev Pathol. 2021; 24 (1): 73-79. doi: 10.1177/1093526620972589.

  18. Abdullah B, Mahmmood V, Museedi O, Hameedi A. Primordial odontogenic tumor: A case report with a novel clinical presentation. J Oral Maxillofac Surg Med Pathol. 2021; 33 (2): 239-42. DOI: 10.1016/j.ajoms.2020.10.003.

  19. Bologna-Molina R, Mikami T, Pereira-Prado V, Pires FR, Carlos-Bregni R, Mosqueda-Taylor A. Primordial odontogenic tumor: An immunohistochemical profile. Med Oral Patol Oral Cir Bucal. 2017; 22 (3): e314-e323. doi: 10.4317/medoral.21859.

  20. Bologna-Molina R, Mikami T, Pereira-Prado V, Tapia-Repetto G, Pires FR, Carlos R et al. Primordial odontogenic tumor: subepithelial expression of Syndecan-1 and Ki-67 suggests origin during early odontogenesis. Oral Dis. 2018; 24 (1-2): 72-77. doi: 10.1111/odi.12733.

  21. Almazyad A, Collette D, Zhang D, Woo SB. Recurrent primordial odontogenic tumor: epithelium-rich variant. Head Neck Pathol. 2022; 16 (2): 550-559. doi: 10.1007/s12105-021-01354-0.

  22. Chrcanovic BR, Brennan PA, Rahimi S, Gomez RS. Ameloblastic fibroma and ameloblastic fibrosarcoma: a systematic review. J Oral Pathol Med. 2018; 47 (4): 315-325. doi: 10.1111/jop.12622.

  23. Kaffe I, Buchner A. Radiologic features of central odontogenic fibroma. Oral Surg Oral Med Oral Pathol. 1994; 78 (6): 811-818. doi: 10.1016/0030-4220(94)90101-5.

  24. Zia M, Arshad A, Zaheer Z. Central odontogenic fibroma: a case report. Cureus. 2018; 10 (4): e2556. doi: 10.7759/cureus.2556.

  25. Noffke CE, Raubenheimer EJ, Chabikuli NJ, Bouckaert MM. Odontogenic myxoma: review of the literature and report of 30 cases from South Africa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007; 104 (1): 101-109. doi: 10.1016/j.tripleo.2007.01.026.

  26. Bologna-Molina R, Mosqueda-Taylor A. Primordial odontogenic tumour or developing odontoma? Histopathology. 2020; 76 (3): 489-490. doi: 10.1111/his.13999.




2020     |     www.medigraphic.com