Bustos RI, L’Gámiz MA, Ochoa SA, Muñoz RFA, García CÁE, González ÁRM, Izunza LAS, Puga OE

Language: Spanish
References: 13
Page: 1-8
PDF size: 359.24 Kb.

ABSTRACT

We report the case of a 39-year-old male patient who debuted with symptoms of neurological deterioration secondary to advanced disease of a long-standing paratesticular tumor without therapeutic approach. Liposarcoma is a malignant mesenchymal tumor of adipose tissue, with a usual presentation of indolent disease and slow growth. Not many cases of advanced disease have been reported in the literature due to the low metastatic potential of this rare histological lineage in paratesticular tumors. The clinical importance of the presented case is due to the diagnostic approach secondary to the deterioration of the patient’s neurological status due to the presence of metastatic disease in the central nervous system. We make a summary of the diagnostic and therapeutic management and characteristics of this pathology.

REFERENCES

1. Chowdhry VK, Kane JM, Wang K, JoyceD, Grand’Maison A, Mann GN. Testicular,Spermatic Cord, and Scrotal Soft TissueSarcomas: Treatment Outcomes and Patterns ofFailure. Sarcoma. 2021;2021: 8824301. https://doi.org/10.1155/2021/8824301.

2. Fitzgerald S, Maclennan GT. Paratesticularliposarcoma. The Journal of Urology. 2009;181(1): 331–332. https://doi.org/10.1016/j.juro.2008.10.080.

3. World Health Organization. Soft Tissue and BoneTumours WHO Classification of Tumours.. 5thed. France: World Health Organization; 2020.

4. Sbaraglia M, Bellan E, Dei Tos AP. The 2020 WHOClassification of Soft Tissue Tumours: news andperspectives. Pathologica. 2021;113(2): 70–84.https://doi.org/10.32074/1591-951X-213

5. Ayari Y, Sellami A, Boussaffa H, Zehani A,Ben Rhouma S, Nouira Y. About a case ofparatesticular myxoid liposarcoma. UrologyCase Reports. 2018;21: 27–28. https://doi.org/10.1016/j.eucr.2018.08.011

6. Tan C, Dasari B, Smyth J, Brown R. Liposarcomaof the spermatic cord: a report of two cases.Annals of The Royal College of Surgeons ofEngland. 2012;94(1): e10–e12. https://doi.org/10.1308/003588412X13171221498901.

7. Gimeno Aránguez M, Escribano Patiño G,Hernández Fernández C, Alvarez FernándezE. Liposarcomas paratesticulares: Estudioclinicopatológico de tres casos y revisión dela literatura. Archivos Españoles de Urología.2006;59(9): 875–881.

8. 8, Kamitani R, Matsumoto K, Takeda T, MizunoR, Oya M. Optimal treatment strategy forparatesticular liposarcoma: retrospectiveanalysis of 265 reported cases. InternationalJournal of Clinical Oncology. 2020;25(12):2099–2106. https://doi.org/10.1007/s10147-020-01753-3.

9. Paulette ÁBM, Carlos ÁFJ, Eduardo AQD.Liposarcoma desdiferenciado del cordónespermático. Revista Mexicana de Urología.2012;72(6): 307–309.

10. Muhsen BA, Ghzawi A, Fares AS, Al-HussainiM, Salah S. Metastatic myxoid liposarcomaof the brain: a case report and review of theliterature. Future Science OA. 7(10): FSO756.https://doi.org/10.2144/fsoa-2021-0077.

11. Zeitouni L, Rahman S, Chan K, Thway K,Arora A, Hammadeh MY. A case report ofuncommon paratesticular liposarcoma ofspermatic cord presenting as a scrotal mass.Urology Case Reports. 2020;33: 101416. https://doi.org/10.1016/j.eucr.2020.101416.

12. Coleman J, Brennan MF, Alektiar K, Russo P.Adult spermatic cord sarcomas: managementand results. Annals of Surgical Oncology.2003;10(6): 669–675. https://doi.org/10.1245/aso.2003.11.014.

13. Italiano A, Toulmonde M, Cioffi A, Penel N,Isambert N, Bompas E, et al. Advanced welldifferentiated/dedifferentiated liposarcomas:role of chemotherapy and survival. Annals ofOncology: Official Journal of the EuropeanSociety for Medical Oncology. 2012;23(6):1601–1607. https://doi.org/10.1093/annonc/mdr485.