Torres-Pinedo CE, Gerardo-del HMN, Fernández-Valiñas S, Rendón-Macías ME

Language: Spanish
References: 21
Page: 12-16
PDF size: 305.93 Kb.

ABSTRACT

Introduction: intestinal perforation in premature or low birth weight neonates can occur spontaneously (SIP) or secondary to necrotizing enterocolitis (NEC); distinguish between these two etiologies based on clinical presentation is challenging. Objective: to compare the medical history, clinical characteristics, progression, and treatment outcomes between neonates with SIP and NEC. Material and methods: a cross-sectional comparative study was conducted on the clinical, surgical, and histopathological characteristics of five neonates with SIP and seven with stage IIIB NEC. Results: the clinical history and progression were similar among all patients, except for fewer gestational weeks at birth in neonates with SIP (27 weeks vs 30 weeks). Histopathological analysis revealed more extensive areas of acute inflammation and necrosis in NEC, with a higher rate of complications compared to SIP (71.4% vs 40%). Conclusions: the clinical presentations of neonates with SIP and NEC are very similar, and diagnosis is typically made through surgical and histopathological findings. Prognosis was less favorable in patients with NEC.

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