medigraphic.com
SPANISH

Cirujano General

ISSN 2594-1518 (Electronic)
ISSN 1405-0099 (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2024, Number 4

<< Back Next >>

Cir Gen 2024; 46 (4)

Complete diagnostic protocol in a patient with GIST

Campos-Campos SF, Campos-Palacios IT, Silva-Castro LG, Barragán-Otero J, Soria-Céspedes D, Villavicencio-Pérez MF
Full text How to cite this article 10.35366/118867

DOI

DOI: 10.35366/118867
URL: https://dx.doi.org/10.35366/118867

Language: Spanish
References: 15
Page: 263-268
PDF size: 384.60 Kb.


Key words:

gastrointestinal bleeding, anemia, melena, hematochezia, tyrosine kinase inhibitor, gastrointestinal stromal tumor.

ABSTRACT

Gastrointestinal bleeding is a medical emergency that requires immediate attention, considering age and comorbidities. Symptoms range from anemia to melena. It uses panendoscopy as an initial evaluation method. If this is negative, use capsule endoscopy. Gastrointestinal stromal tumors are mainly benign, although 30% are malignant, located in the stomach and small intestine. The first-line intervention treatment is surgical resection and imatinib as therapy. We describe the case of a 51-year-old female patient admitted for burning and colic epigastric pain, nausea, pallor, and multiple melena stools. We transfuse two red blood cell concentrates. After clinical deterioration, different tests were performed, including capsule endoscopy to identify non-visible bleeding and enteroscopy to mark the lesions detected through the capsule. We performed a diagnostic laparoscopy where a subepithelial tumor of the proximal jejunum was identified and resected. Histopathological analysis reveals a low-risk gastrointestinal stromal tumor with negative margins. We referred the patient to oncology for follow-up. Tests such as capsule endoscopy and enteroscopy allow identification of the origin of bleeding in the mid-gastrointestinal tract, as described in this report.


REFERENCES

  1. Campos-Campos SF. Hemorragia de tubo digestivo alto. En: Campos Campos Salvador Francisco. Gutiérrez-Arrubarrena Fisiopatología quirúrgica del aparato digestivo. Editorial El Manual Moderno. 4ª ed. Campos Campos Salvador Francisco, editor. 2012. p. 240-250.

  2. Téllez AF, García OS, Borjas AO. Sangrado del tracto digestivo medio. In: Nahum M, editor. Gastroenterología. 4th ed. McGraw-Hill Education; 2022. Disponible en: https://accessmedicina.mhmedical.com/content.aspx?bookid=3246§ionid=272453592

  3. Ribeiro I, Pinho R, Rodrigues A, Fernandes C, Silva J, Ponte A, Tente D, Carvalho J. The importance of alternative diagnostic modalities in the diagnosis of small bowel tumors after a negative capsule endoscopy. GE - Port J Gastroenterol. 2015; 22: 303-310. Available in: https://www.elsevier.es/en-revista-ge-portuguese-journal-gastroenterology-347-articulo-the-importance-alternative-diagnostic-modalities-S2341454515000149

  4. Zavala-Gutiérrez R. Sangrado de tubo digestivo medio secundario a tumor del estroma gastrointestinal. Cir Gen. 2021; 18: 41-45. Disponible en: https://doi.org/10.35366/103915

  5. Kwaan MR, Stewart DB, Dunn K. Colon, recto y ano. En: Brunicardi F, Andersen DK, Billiar TR, Dunn DL, Kao LS, Hunter JG, et al. Schwartz. Principios de Cirugía. 11th ed. McGraw-Hill Education; 2020. Disponible en: https://accessmedicina.mhmedical.com/content.aspx?bookid=2958§ionid=250641340

  6. Ramos JJA, Espinoza Ríos J, Valdivia JLP, Salas Dueñas Y, Morgan RC. Mid-gastrointestinal bleeding secondary to a gastrointestinal stromal tumor of the jejunum: a case report. Rev Gastroenterol Mex. 2019; 84: 60-63. Available from: https://doi.org/10.1016/j.rgmxen.2019.02.002

  7. Navarro-Tovar F, Hernández-Pérez E, Carzolio-Trujillo HA, Aguilar-Priego JM, Hernández-Martínez IA, García-Salazar JM. Hemorragia de tubo digestivo secundaria a tumor del estroma gastrointestinal localizado en yeyuno. Gac Mex Oncol. 2016; 12: 165-169. Disponible en: https://doi.org/10.1016/j.gamo.2016.09.012

  8. Tests for Gastrointestinal Stromal Tumors. American Cancer Society [Internet]. Available in: https://www.cancer.org/cancer/types/gastrointestinalstromal-tumor/detection-diagnosis-staging/how-diagnosed.html

  9. Burch J. Gastrointestinal Stromal Cancer. StatPearls [Internet]. U.S. National Library of Medicine; 2022. Available in: https://www.ncbi.nlm.nih.gov/books/NBK554541/

  10. Mantese G. Gastrointestinal stromal tumor. Curr Opin Gastroenterol. 2019; 35: 555-559. Available in: https://doi.org/10.1097/mog.0000000000000584

  11. Parab TM, DeRogatis MJ, Boaz AM, Grasso SA, Issack PS, Duarte DA, et al. Gastrointestinal stromal tumors: a comprehensive review. J Gastrointest Oncol. 2018; 9: 144-154. Available in: https://doi.org/10.21037/jgo.2018.08.20

  12. Xu X, Cao Z, Zhu H. Capsule endoscopy in the diagnosis of an exophytic gastrointestinal stromal tumor in the small intestine of a young adult woman: a case report. Mol Clin Oncol. 2015; 3: 1289-1291. Available in: https://doi.org/10.3892/mco.2015.697

  13. National Institutes of Health (NIH). Tratamiento de los tumores de estroma gastrointestinal (PDQ®) [Internet]. Cancer.gov; 2023. Available from: https://www.cancer.gov/espanol/tipos/sarcoma-de-tejido-blando/pro/tratamiento-tegi-pdq

  14. Tartaglia D, Mazzoni A, Puglisi AG, Coccolini F, Chiarugi M. Intraoperative enteroscopy for the identification of obscure bleeding source caused by gastrointestinal angiodysplasias: through a balloon-tip trocar is better. Colorectal Dis. 2020; 22: 561-568. Available in: https://doi.org/10.1111/codi.15348

  15. Lin JX, Chen QF, Zheng CH, Li P, Xie JW, Wang JB, et al. Is 3-years duration of adjuvant imatinib mesylate treatment sufficient for patients with high-risk gastrointestinal stromal tumor? A study based on long-term follow-up. J Cancer Res Clin Oncol. 2017; 143: 727-734. Available in: https://doi.org/10.1007/s00432-017-2363-4




Figure 1
Figure 2
Figure 3
Table 1

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Cir Gen. 2024;46