2024, Number 4
Complete diagnostic protocol in a patient with GIST
Language: Spanish
References: 15
Page: 263-268
PDF size: 384.60 Kb.
ABSTRACT
Gastrointestinal bleeding is a medical emergency that requires immediate attention, considering age and comorbidities. Symptoms range from anemia to melena. It uses panendoscopy as an initial evaluation method. If this is negative, use capsule endoscopy. Gastrointestinal stromal tumors are mainly benign, although 30% are malignant, located in the stomach and small intestine. The first-line intervention treatment is surgical resection and imatinib as therapy. We describe the case of a 51-year-old female patient admitted for burning and colic epigastric pain, nausea, pallor, and multiple melena stools. We transfuse two red blood cell concentrates. After clinical deterioration, different tests were performed, including capsule endoscopy to identify non-visible bleeding and enteroscopy to mark the lesions detected through the capsule. We performed a diagnostic laparoscopy where a subepithelial tumor of the proximal jejunum was identified and resected. Histopathological analysis reveals a low-risk gastrointestinal stromal tumor with negative margins. We referred the patient to oncology for follow-up. Tests such as capsule endoscopy and enteroscopy allow identification of the origin of bleeding in the mid-gastrointestinal tract, as described in this report.REFERENCES
Ribeiro I, Pinho R, Rodrigues A, Fernandes C, Silva J, Ponte A, Tente D, Carvalho J. The importance of alternative diagnostic modalities in the diagnosis of small bowel tumors after a negative capsule endoscopy. GE - Port J Gastroenterol. 2015; 22: 303-310. Available in: https://www.elsevier.es/en-revista-ge-portuguese-journal-gastroenterology-347-articulo-the-importance-alternative-diagnostic-modalities-S2341454515000149
Navarro-Tovar F, Hernández-Pérez E, Carzolio-Trujillo HA, Aguilar-Priego JM, Hernández-Martínez IA, García-Salazar JM. Hemorragia de tubo digestivo secundaria a tumor del estroma gastrointestinal localizado en yeyuno. Gac Mex Oncol. 2016; 12: 165-169. Disponible en: https://doi.org/10.1016/j.gamo.2016.09.012
Tartaglia D, Mazzoni A, Puglisi AG, Coccolini F, Chiarugi M. Intraoperative enteroscopy for the identification of obscure bleeding source caused by gastrointestinal angiodysplasias: through a balloon-tip trocar is better. Colorectal Dis. 2020; 22: 561-568. Available in: https://doi.org/10.1111/codi.15348
Lin JX, Chen QF, Zheng CH, Li P, Xie JW, Wang JB, et al. Is 3-years duration of adjuvant imatinib mesylate treatment sufficient for patients with high-risk gastrointestinal stromal tumor? A study based on long-term follow-up. J Cancer Res Clin Oncol. 2017; 143: 727-734. Available in: https://doi.org/10.1007/s00432-017-2363-4