Díaz-Aguilar FA, Casimiro-Pita MI, Mendez-Jesus IA, Martínez-Rodríguez PB, Cuéllar-Alcántar A, Sánchez-Franco B

Language: Spanish
References: 12
Page: 179-185
PDF size: 816.32 Kb.

ABSTRACT

Sepsis is defined as “organ dysfunction caused by an abnormal host response to infection.” It consists of a state of exacerbated inflammation that develops in response to a pathogen. Objective: the prevalence of morbidity and mortality of patients with sepsis in the adult intensive care unit of the UMAE Hospital of Gynecology and Obstetrics N° 3 was measured. Material and methods: observational, descriptive, retrospective and cross-sectional study, all records of patients admitted with a diagnosis of sepsis in the period from March 31, 2012 to April 1, 2017 were included. With data collection, the description and observation of the results was carried out; the SPSS 20 program was used for analysis. Results: a total of 64 patients were registered, the average age was 42 years. The average stay of patients in intensive care was 7 days, it was found that 15.6% of patients did not present comorbidities at the time of admission and 84.4% of patients (n=54) presented at least one comorbidity. The site most frequently found as a source of infection was found in the abdomen, corresponding to 67.18%. Of the total records reviewed, 31.3% belonged to pregnant or postpartum women, with the infectious focus found most frequently in these patients being the upper respiratory tract. The main microorganism isolated was Escherichia coli, being isolated in 12.5% of the cases. Conclusions: with the results found, we can deduce that cultures are not taken routinely, since 35.9% of patients in our study did not have them, of this total 62% corresponded to patients with sepsis of abdominal focus, 29.1% . to patients with respiratory focus; Targeted empirical antibiotic therapy is indicated and subsequently a change in antibiotic regimens is necessary, also taking into account the clinical picture.

REFERENCES

1. Dellinger RP, Levy M, Rhodes A, et al. Surviving Sepsis Campaign:International Guidelines for Management of Severe Sepsis andSeptic. Shock: 2012. Critical Care Medicine 2013; 41:2580-637.

2. Singer M, Deutschman CS, Seymour CW et al. The third internationalConsensus Definitions for Septic Shock. JAMA 2016;

3. 315:801-810.3. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. IntensiveCare Med. 2003;29:530-538.

4. Shankar-Hari M, Phillips G, Levy ML, et al. Assessment of definitionand clinical criteria for septic shock. JAMA.2016.0289.

5. Diagnóstico y tratamiento de Sepsis Grave y Choque Séptico enel adulto. México: Secretaria de Salud; 2009.

6. Martin GS, Mannino DM, Eaton S. et al. The epidemiology of sepsisin the United States from1979 through 2000. New England andJournal Medicine 2003; 348:1546-554.

7. Tupchong K, Koyfman A, Foran M. Sepsis, severe sepsis and septicshock: A review of the literature. African Journal of EmergencyMedicine 2015; 5: 127–135.

8. Martin-Ramírez JF, Domínguez-Borgua A, Vázquez-Flores AD.Sepsis. Medicina Interna México 2014;30:159-175.

9. Munford RS, Suffredini AF. Sepsis, Sepsis Grave y Choque Séptico.En: Mendell, Douglas y Bannett. Enfermedades infecciosasprincipios y práctica 8va ed, Elsevier 2015: 949-971

10. Carrillo R, Tapia J, Peña CA, et al. Bases Moleculares de la Sepsis.Fac. Med. UNAM 2014; 57(3):9-21

11. Cawcutt KA, Peters SG. Severe Sepsis and Septic Shock: ClinicalOverview and Update on Management. Mayo Clin Proc.2014;89:1572-1578.

12. Gorordo.Delsol L, Perez-Nieto O, Porras-Escorcia O, et al. Sepsisabdominal: Fisiopatología Diagnóstico y tratamiento; Rev Mex. deCirugía de aparato Digestivo, 2015; 4:110-117.