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2025, Number 1

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Acta Med 2025; 23 (1)

Prevalence of adenomyosis in patients exposed to hyperestrogenism with a diagnosis of uterine myomatosis, according to the theory of invagination as an etiology of adenomyosis

López LCA, González BM, Guzmán VG, Arredondo MR
Full text How to cite this article 10.35366/119345

DOI

DOI: 10.35366/119345
URL: https://dx.doi.org/10.35366/119345

Language: Spanish
References: 12
Page: 28-31
PDF size: 224.58 Kb.


Key words:

hyperestrogenism, adenomyosis, uterine myomatosis.

ABSTRACT

Introduction: abnormal uterine bleeding is the first cause of gynecological consultation in fertile age. It has several etiologies (PALM COEIN) and one of the most important is myomatosis and adenomyosis, where the relationship is hyperestrogenism. Objective: demonstrate the relationship between uterine myomatosis and adenomyosis as a consequence of the same etiology, hyperestrogenism. Material and methods: retrospective, observational, descriptive and case-control design, in which 655 clinical records of patients undergoing abdominal hysterectomy with post-surgical pathology results were collected. The procedures were carried out in the period from March 1, 2017 to March 1, 2019, in a private tertiary hospital, Hospital Angeles Pedregal in Mexico City, Mexico. Results: we found that the prevalence of uterine myomatosis and adenomyosis in two years at the Angeles Pedregal Hospital is 31.9%. Conclusions: the etiology of intussusception secondary to hyperestrogenism is related to both pathologies, demonstrating a prevalence of both in 31.9% of the patients studied. Age or pregnancies were not significant during the study.


REFERENCES

  1. Fernández-Díaz JM. Correlación entre el diagnóstico ecográfico e histopatológico de adenomiosis en pacientes histerectomizadas en el Hospital Nacional Arzobispo Loayza del 2017 al 2021. Handlenet. 2022. Disponible en: https://hdl.handle.net/20.500.12866/11995

  2. Bacon JL. Abnormal uterine bleeding: current classification and clinical management. Obstet Gynecol Clin North Am. 2017; 44 (2): 179-193.

  3. Hernández-Valencia M, Valerio-Castro E, TerceroValdez-Zúñiga CL, Barrón-Vallejo J, Luna-Rojas RM. Miomatosis uterina: implicaciones en salud reproductiva. Ginecol Obstet Mex. 2017; 85 (9): 611-633.

  4. Taran FA, Weaver AL, Coddington CC, Stewart EA. Characteristics indicating adenomyosis coexisting with leiomyomas: a case-control study. Hum Reprod. 2010; 25 (5): 1177-1182. doi: 10.1093/humrep/deq034.

  5. García-Solares J, Donnez J, Donnez O, Dolmans MM. Pathogenesis of uterine adenomyosis: invagination or metaplasia? Fertil Steril. 2018; 109 (3): 371-379.

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  7. Galicia TLN, Gómez PMG. Prevalencia de adenomiomas y hallazgos asociados en estudios de resonancia magnética de útero en pacientes con miomatosis. Acta Med. 2022; 20 (1): 24-29.

  8. Khalifa T, Abidalla K, Al-Zail N. The significance of pain in leiomyoma with adenomyosis and liomyoma without adenomysis. Tobruk University Journal of Medical Sciences (TUJMS). 2023; 5 (1): 63-69.

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  10. Brun JL, Creux H, Gauzere R, Randaoharison P, Dallay D. Tratamiento de la adenomiosis. EMC - Ginecología-Obstetricia. 2007; 43 (3): 1-9.

  11. Pron G, Cohen M, Soucie J, Garvin G, Vanderburgh L, Bell S. The Ontario Uterine Fibroid Embolization Trial. Part 1. Baseline patient characteristics, fibroid burden, and impact on life. Fertil Steril. 2003; 79 (1): 112-119.

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Acta Med. 2025;23