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2025, Number 1

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Acta Med 2025; 23 (1)

Vulvar myoepithelioma

Martínez RM, Velázquez SM, Núñez AH, Soto ACE, Galicia GCE
Full text How to cite this article 10.35366/119356

DOI

DOI: 10.35366/119356
URL: https://dx.doi.org/10.35366/119356

Language: Spanish
References: 5
Page: 67-68
PDF size: 171.19 Kb.


Key words:

myoepithelioma, SMARCB1 tumor, soft tissue tumor, vulvar neoplasia.

ABSTRACT

31-year-old female comes to her annual check-up; during a vaginal exam, a vulvar tumor is observed, and an additional biopsy is taken with the report of myoepithelium. The tumor is positive for vimentin, cytokeratin, and progesterone receptors. The tumor resection was reported with free edges. Myoepitheliomas are rare soft tissue tumors related to a genetic alteration associated with sarcomas with poor prognosis. However, the genital area is primarily benign.


REFERENCES

  1. Yoshida A, Yoshida H, Yoshida M, Mori T, Kobayashi E, Tanzawa Y et al. Myoepithelioma-like tumors of the vulvar region: a distinctive group of SMARCB1-deficient neoplasms. Am J Surg Pathol. 2015; 39 (8): 1102-1113.

  2. Gleason B, Hornick JL. Myoepithelial tumours of skin and soft tissue: an update. Diagnostic Histopathology. 2008, 14 (11): 552-562.

  3. Meenakshi M, McCluggage WG. Myoepithelial neoplasms involving the vulva and vagina: report of 4 cases. Hum Pathol. 2009; 40 (12): 1747-1753.

  4. McCluggage WG, Stewart CJR. SWI/SNF-deficient malignancies of the female genital tract. Semin Diagn Pathol. 2021; 38 (3): 199-211.

  5. Liu X, Chen L, Zhou Q, Liu J, Hu Y. Myoepithelioma-like tumors of the vulvar region: a case report and review of the literature. J Obstet Gynaecol Res. 2022; 48 (7): 2015-2020.




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C?MO CITAR (Vancouver)

Acta Med. 2025;23