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2024, Number 4

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Rev Mex Pediatr 2024; 91 (4)

In-hospital growth in very low birth weight preterm newborns with and without necrotizing enterocolitis

Acosta-Hernández D, Hernández-Molinero YT, Hernando-Becerra G, Silva-Ramírez H, Rendón-Macías ME

Language: Spanish
References: 22
Page: 134-141
PDF size: 350.92 Kb.


ABSTRACT

Introduction: necrotizing enterocolitis (NEC) is an intestinal complication that limits nutrition and can compromise growth and neurodevelopment in very low birth weight preterm newborns (VLBW). Objective: to determine the impact of NEC on the intra-hospital weight growth of VLBW infants. Material and methods: Case-cohort study with 199 VLBW infants, grouped into those with and without NEC. Each patient was followed for at least 21 weeks, recording their weight gain. Other study variables were weeks of gestational age at birth (GAB), age of presentation and severity of NEC, use of probiotics, type of feeding: parenteral nutrition (TPN) or enteral. Results: there were no differences between the groups in terms of sex and GEF. Neonates with NEC had lower birth weight (mean 1,165 g, versus 1,255 g, p = 0.003), received less probiotics (17.5 versus 59.6%, p < 0.001) and had fewer days hospitalized (median 62 versus 44, p < 0.001). 98.5% received TPN in the first week and began enteral stimulation on the fourth day. Cumulative weight growth was similar in both groups; total gain at 21 days was, on average, 318 g (cases) versus 299.3 g (controls), p = 0.49. Conclusions: it is likely that adequate nutrition from the first days of life, with recommended caloric intake, has allowed newborns with NEC to maintain their growth in a similar way to those who did not present NEC.


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