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Acta de Otorrinolaringología & Cirugía de Cabeza y Cuello

ISSN 2539-0859 (Electronic)
ISSN 0120-8411 (Print)
Asociación Colombiana de Otorrinolaringología y Cirugía de Cabeza y cuello, Maxilofacial y Estética Facial (ACORL)
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2024, Number 4

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Acta de Otorrinolaringología CCC 2024; 52 (4)

Protocol and consent for intratympanic injection

Ordóñez OLE, Cruz CSE, Guzmán DJE, Silva RR
Full text How to cite this article

Language: Spanish
References: 15
Page: 650-659
PDF size: 645.21 Kb.


Key words:

Injection, intratympanic, meniere disease, hearing loss, sudden.

ABSTRACT

The intratympanic injection is used to treat cochleovestibular symptoms associated with inner ear diseases such as Ménière’s disease or sudden sensorineural hearing loss. The most commonly used drugs are corticosteroids and aminoglycosides, and recently studies have been published on the use of N-acetylcysteine.


REFERENCES

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  2. Sarafraz Z, Ahmadi A, Daneshi A. Transtympanic Injections of N-acetylcysteine and Dexamethasone for Prevention of Cisplatin-Induced Ototoxicity: Double Blind Randomized Clinical Trial. Int Tinnitus J. 2018;22(1):40-45. doi: 10.5935/0946-5448.20180007

  3. Sturm JJ, Maurrasse SE, Golub JS. Intratympanic steroid injection. Oper Tech Otolayngol Head Neck Surg. 2021;32(2):92–8. doi:10.1016/j.otot.2021.05.005

  4. Ordóñez Ordóñez LE, Mojica Rojas AM. Fisiología coclear. Acta otorrinolaringol cir cabeza cuello. 2017;43(3):187-210. doi:10.37076/acorl.v43i3.29

  5. Lukashkin AN, Sadreev II, Zakharova N, Russell IJ, Yarin YM. Local Drug Delivery to the Entire Cochlea without Breaching ItsBoundaries. iScience. 2020;23(3):100945. doi: 10.1016/j.isci.2020.100945

  6. El Kechai N, Agnely F, Mamelle E, Nguyen Y, Ferrary E, Bochot A. Recent advances in local drug delivery to the inner ear. Int JPharm. 2015;494(1):83-101. doi: 10.1016/j.ijpharm.2015.08.015

  7. Nyberg S, Abbott NJ, Shi X, Steyger PS, Dabdoub A. Delivery of therapeutics to the inner ear: The challenge of the blood-labyrinthbarrier. Sci Transl Med. 2019;11(482):eaao0935. doi: 10.1126/scitranslmed.aao0935

  8. Hamid M, Trune D. Issues, indications, and controversies regarding intratympanic steroid perfusion. Curr Opin Otolaryngol HeadNeck Surg. 2008;16(5):434-40. doi: 10.1097/MOO.0b013e32830ce796

  9. Patel M. Intratympanic corticosteroids in Ménière’s disease: A mini-review. J Otol. 2017;12(3):117-124. doi: 10.1016/j.joto.2017.06.002

  10. Devantier L, Djurhuus BD, Hougaard DD, Händel MN, Guldfred FL, Schmidt JH, et al. Intratympanic Steroid for Menière’s Disease:A Systematic Review. Otol Neurotol. 2019;40(6):806-12. doi: 10.1097/MAO.0000000000002255

  11. Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, et al. Clinical Practice Guideline: SuddenHearing Loss (Update). Otolaryngol Head Neck Surg. 2019;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885

  12. Staecker H, Morelock M, Kramer T, Chrbolka P, Ahn JH, Meyer T. Safety of Repeated-Dose Intratympanic Injections with AM-101in Acute Inner Ear Tinnitus. Otolaryngol Head Neck Surg. 2017;157(3):478-487. doi: 10.1177/0194599817711378

  13. Bodmer D, Morong S, Stewart C, Alexander A, Chen JM, Nedzelski JM. Long-term vertigo control in patients after intratympanicgentamicin instillation for Ménière’s disease. Otol Neurotol. 2007;28(8):1140-4. doi: 10.1097/mao.0b013e31815aea05

  14. Liu YC, Chi FH, Yang TH, Liu TC. Assessment of complications due to intratympanic injections. World J Otorhinolaryngol HeadNeck Surg. 2016;2(1):13-6. doi: 10.1016/j.wjorl.2015.11.001

  15. de Cates C, Winters R. Intratympanic Steroid Injection. [Actualizado el 4 de julio de 2023]. En: StatPearls [Internet]. Treasure Island(FL): StatPearls Publishing; 2024. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK567708/




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C?MO CITAR (Vancouver)

Acta de Otorrinolaringología CCC. 2024;52