2025, Number 1
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Dermatología Cosmética, Médica y Quirúrgica 2025; 23 (1)
Malignant chondroid syringoma. A case report
Nivón CC, Vázquez VR, Espinoza HCJ, Íñigo GK
Language: Spanish
References: 12
Page: 28-32
PDF size: 250.13 Kb.
ABSTRACT
Malignant chondroid syringoma (MCS) is a very rare adnexal tumor
that originates from the sweat glands of the skin. Clinical diagnosis
is challenging due to the lack of clear criteria for its identification.
For this reason, histopathological examination is an important
part for establishing the diagnosis. MCS displays a characteristic
biphasic pattern of epithelial and mesenchymal components. The
use of immunostaining serves as an auxiliary tool by demonstrating
positivity in different markers depending on cell differentiation.
The prognosis of this tumor depends on the location, age, and sex
of the patient; primary tumors on the trunk of older female patients
are associated with a worse prognosis. Wide local excision
is the treatment of choice. We present the case of an 82-year-old
woman with an asymptomatic, rapidly growing lesion on her back.
The tumor was excised and sent for histopathologic examination,
where the diagnosis of MCS was established.
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