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2025, Number 3

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Acta Med 2025; 23 (3)

Physiological variables in patients undergoing endoscopy under sedation with fentanyl compared with remifentanil

Rodríguez CBC, Rusz ACI

Language: Spanish
References: 42
Page: 231-237
PDF size: 236.17 Kb.


ABSTRACT

Introduction: sedation and analgesia are essential in endoscopic procedures, but it is crucial to consider the cardiovascular effects of the agents used. Appropriate agent selection and ongoing monitoring are key to ensuring patient safety and a successful recovery. Objective: to identify changes in the hemodynamic status of the patient undergoing endoscopic procedure under sedation-analgesia with remifentanil compared to fentanyl. Material and methods: an observational, analytical, retrospective study was carried out on patients who underwent an endoscopic procedure under sedation-analgesia with remifentanil or fentanyl in the period January 2021 to December 2022. Information of interest was extracted, including Ramsay blood pressure, heart rate, respiratory rate, and oxygen saturation before sedation and subsequent until discharge. A descriptive and inferential statistical analysis was performed. A value of p < 0.05 was considered significant. Results: 121 patients were included, of which 28 received remifentanil, and 92 received fentanyl to provide sedation for colonoscopy and panendoscopy. Blood pressure was significantly lower in those who received remifentanil than in those who received fentanyl at 5 minutes after administration-no other significant differences. The incidence of hypotension in group R was 7.1%, and in group F was 2.2% (p = 0.436). At the same time, the incidence of hypertension during the procedure was 3.6% in group R and 3.6% in group F (p = 0.468). Conclusion: remifentanil and fentanyl presented a similar profile of sedative efficacy and safety.


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