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2025, Number 3

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Acta Med 2025; 23 (3)

Neutrophil-to-lymphocyte ratio as a predictor of complicated acute appendicitis in patients from Hospital Angeles Pedregal. Letter to the editor

Saucedo MEM
Full text How to cite this article 10.35366/119970

DOI

DOI: 10.35366/119970
URL: https://dx.doi.org/10.35366/119970

Language: Spanish
References: 5
Page: 310-311
PDF size: 147.96 Kb.


Key words:

appendicitis, complication, comment.

The study analyzes the relationship between the neutrophil-to-lymphocyte ratio and complicated acute appendicitis. However, the use of ROC curves to assess sensitivity and specificity does not address the stated objective. Methodological errors were identified in the interpretation of results and the statistical tests used. Additionally, the conclusions lack support, as the reported specificity is low. It is recommended to adjust the study design and analysis to obtain more accurate conclusions.


REFERENCES

  1. Alanis-Rivera B, Zúñiga-Vázquez LA, Silva-Escamilla MC. Hiperbilirrubinemia como factor predictivo de apendicitis perforada. Rev Med Inst Mex Seguro Soc. 2016; 54 (5): 552-561.

  2. Rebollar-González RC, García-Álvarez J, Trejo-Téllez R. Apendicitis aguda: revisión de la literatura. Rev Hosp Jua Mex. 2009; 76 (4): 210-216.

  3. Avanesov M, Wiese NJ, Karul M, Guerreiro H, Keller S, Busch P et al. Diagnostic prediction of complicated appendicitis by combined clinical and radiological appendicitis severity index (APSI). Eur Radiol. 2018; 28 (9): 3601-3610. doi: 10.1007/s00330-018-5339-9.

  4. Talavera JO, Wacher-Rodarte NH, Rivas-Ruiz R. Estudios de proceso (prueba diagnóstica). Rev Med Inst Mex Seguro Soc. 2013; 51 (Supl): S16-S23.

  5. García-Amador C, Arteaga-Peralta V, de la Plaza-Llamas R, Torralba M, Medina-Velasco A, Ramia JM. Valoración de parámetros clínicos y analíticos preoperatorios en apendicitis aguda complicada. Score para predecir apendicitis complicada. Cir Esp. 2021; 99 (4): 282-288.




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Acta Med. 2025;23