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Federación Mexicana de Ginecología y Obstetricia, A.C.

2025, Number 4

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Ginecol Obstet Mex 2025; 93 (4)

Advancements in the management of postpartum hemorrhage: a semi-systematic review

Briones GJC

Language: Spanish
References: 35
Page: 152-163
PDF size: 380.42 Kb.


ABSTRACT

Background: Postpartum hemorrhage remains a leading cause of maternal mortalityworldwide. In Mexico, postpartum hemorrhage was the leading cause of direct maternal death in 2023.
Objective: To review the medical care of patients with postpartum hemorrhage and new technologies such as the JADA system.
Methodology: A semi-systematic review that included articles in English and Spanish of the type of controlled clinical trials, cohort and observational studies with a publication date in the last 11 years (2014 to 2024). The reference search was limited to the PubMed-Medline database, with the search strategy defined by the keywords (MeSH): "hemorrhage/prevention & control", "hemorrhage/therapy".
Results: 1083 articles were identified. In the first stage of the selection process (title and abstract), 300 articles were retained. In the second phase (full text), 35 were selected and the rest were rejected for not being directly related to postpartum hemorrhage, duplicate articles, studies with weak methodology, or not relevant.
Conclusions: The choice of treatment depends on the severity and cause of the bleeding, the patient's response to initial general treatment, and the availability of resources and specialized medical equipment. It may include a combination of noninvasive or invasive measures, ranging from homeostatic treatment to surgical intervention. Evidence has shown that the intrauterine vacuum-controlled hemorrhage device has the potential to be used early to rapidly and effectively control postpartum hemorrhage.


REFERENCES

  1. Escobar MF, Nassar AH, Theron G, et al. FIGO recommendationson the management of postpartum hemorrhage 2022. Int J Gynecol Obstet 2022; 157 Suppl 1(Suppl 1):3-50. https://doi.org/10.1002/ijgo.14116

  2. Say L, Chou D, Gemmill A, et al. Global causes of maternaldeath: a WHO systematic analysis. Lancet Glob Health2014; 2(6): e323-333. https://doi.org/10.1016/S2214-109X(14)70227-X

  3. WHO. Maternal Mortality. [Internet] OMS, 2023 [citada 26de abril de 2024]. Mortalidad materna (who.int)

  4. Calvert C, Thomas SL, Ronsmans C, et.al. IdentifyingRegional Variation in the Prevalence of PostpartumHaemorrhage: A Systematic Review and Meta-Analysis.PLoS ONE 2012; 7(7): e41114. https://doi.org/10.1371/journal.pone.0041114

  5. Haeri S, Dildy GA. Maternal Mortality From Hemorrhage.Semin Perinatol 2012; 36(1): 48-55. https://doi.org/10.1053/j.semperi.2011.09.010

  6. CENETEC. Prevención y manejo de la hemorragia postparto.Guía de Práctica Clínica: Evidencias y Recomendaciones.México; 2021. http://www.cenetec-difusion.com/CMGPC/GPC-SS-103-21/ER.pdf3_OMS

  7. Dirección General de Epidemiología. Informe Semanalde Notificación Inmediata de Muerte Materna. InformeSemanal de Vigilancia Epidemiológica, Secretaria de Salud2023: 1-7. https://www.gob.mx/cms/uploads/attachment/file/878706/MM_2023_SE52.pdf

  8. WHO Technical Working Group on the Prevention andManagement of Postpartum Haemorrhage. The preventionand Management of Pospartum haemorrague. Report ofa tecnical working group. Genevam Switzerland; 1989.https://iris.who.int/handle/10665/61409

  9. FIGO. Generic Postpartum Haemorrhage Clinical Protocoland Care Pathways; 2022. https://www.figo.org/news/figo-generic-postpartum-haemorrhage-protocol-and-carepathways-now-available-online

  10. Committee on Practice Bulletins-Obstetrics. PracticeBulletin No. 183: Postpartum hemorrhage. Obstetricsand Gynecology 2017; 130(4): e168-e186. https://doi.org/10.1097/AOG.0000000000002351

  11. Bláha J, Bartosová T. Epidemiology and definition of PPHworldwide. Best Pract Res Clin Anaesthesiol 2022; 36(3-4): 325-339. https://doi.org/10.1016/j.bpa.2022.11.001

  12. Borovac-Pinheiro A, Pacagnella RC, Cecatti JG, et al.Postpartum hemorrhage: new insights for definition anddiagnosis. Am J Obstet Gynecol 2018; 219(2): 162-168.https://doi.org/10.1016/j.ajog.2018.04.013

  13. Higgins N, Patel SK, Toledo P. Postpartum hemorrhagerevisited: new challenges and solutions. Curr OpinAnesthesiol 2019; 32(3): 278-284. https://doi.org/10.1097/ACO.0000000000000717

  14. Committee on Practice Bulletins-Obstetrics. ACOG PracticeBulletin No. 183: Postpartum Hemorrhage. Obstet Gynecol2017; 130(4): e168-e186. https://doi.org/10.1097/AOG.0000000000002351

  15. Robinson D, Basso M, Chan C,et al. Guideline No. 431:Postpartum Hemorrhage and Hemorrhagic Shock. J ObstetGynaecol Can 2022; 44(12): 1293-1310. https://doi.org/10.1016/j.jogc.2022.10.002

  16. Oyelese Y, Ananth CV. Postpartum Hemorrhage: Epidemiology,Risk Factors, and Causes. Clin Obstet Gynecol2010; 53(1): 147-156. https://doi.org/10.1097/GRF.0b013e3181cc406d

  17. Dirección General de Epidemiología. Manual de procedimientosestandarizados para la vigilancia epidemiológicade la morbilidad materna extremadamente grave. Secretariade Salud 2021. 19_Manual_VE_SIVEMorbilidadMaternaSevera.pdf (salud.gob.mx)

  18. Ministerio de Salud y Protección Social. Morbilidad Maternaextrema: Análisis agregado de Casos de 2007 a 2012.Bogotá D.C. 2014. AF MORBILIDAD MATERNA EXTREMAANALISIS AGREGADO DE CASOS DE 2007 A 2012_21,59 X27,94 (minsalud.gov.co)

  19. Lalonde A, Obstetrics IFoGa. Prevention and treatmentof postpartum hemorrhage in low-resource settings. IntJ Gynaecol Obstet 2012; 117(2): 108-118. https://doi.org/10.1016/j.ijgo.2012.03.001

  20. WHO Recommendations for the Prevention and Treatmentof Postpartum Haemorrhage. Geneva: World HealthOrganization; 2012. PMID: 23586122.

  21. Angarita AM, Cochrane E, Bianco A, et al. Prevention ofpostpartum hemorrhage in vaginal deliveries. Eur J ObstetGynecol Reprod Biol 2023;280 : 112-119. https://doi.org/10.1016/j.ejogrb.2022.11.021

  22. Bohlmann MK, Rath W. Medical prevention and treatmentof postpartum hemorrhage: a comparison of differentguidelines. Arch Gynecol Obstet 2014; 289 (3): 555-567.https://doi.org/10..1007/s00404-013-3016-4

  23. FIGO PPH Technical Working Group , Begum F, Beyeza J,Burke T, Evans C, Hanson C, et al. FIGO and the InternationalConfederation of Midwives endorse WHO guidelines onprevention and treatment of postpartum hemorrhage.Int J Gynecol Obstet 2022; 158 (Suppl 1): 6-10. https://doi.org/10.1002/ijgo.14199

  24. Papadopoulou A, Tourna G, Georgiopoulos G, et al. Preventingpostpartum hemorrhage: A network meta-analysison routes of administration of uterotonics. Eur J ObstetGynecol Reprod Biol 2024; 295: 172-180. https://doi.org/10.1016/j.ejogrb.2024.02.021

  25. California Maternal Quality Care Collaboraty (CMQCC).Appendix D: Obstetric Hemorrhage Care Guidelines:Flowchart Format. [Internet].; 2021 [consultado 19 agosto2024]. Appendix D Obstetric Hemorrhage Care GuidelinesFlowchart Format Errata 7.2022_0.pdf (cmqcc.org)

  26. D’Alton ME, Rood KM, Smid MC, et al. IntrauterineVacuum-Induced Hemorrhage-Control Device for RapidTreatment of Postpartum Hemorrhage. Obstet Gynecol2020; 136(5) : 882-891. https://doi.org/10.1097/AOG.0000000000004138

  27. Purwosunu Y, Sarkoen W, Arulkumaran S, et al. Control ofPostpartum Hemorrhage Using Vacuum-Induced UterineTamponade. Obstet Gynecol 2016; 128(1): 33-36. https://doi.org/10.1097/AOG.0000000000001473

  28. Gulersen M, Gerber RP, Rochelson, et al. Vacuum-InducedHemorrhage Control versus Uterine Balloon Tamponadefor Postpartum Hemorrhage. J Obstet GynaecolCan 2023; 45(4): 267-272. https://doi.org/10.1016/j.jogc.2023.02.017

  29. Goffman D, Rood KM, Bianco A, et al. Real-World Utilizationof an Intrauterine, Vacuum-Induced, Hemorrhage-Control Device. Obstet Gynecol 2023; 142(5). https://doi.org/10.1097/AOG.0000000000005366

  30. D'Alton M, Rood K, Simhan H, et al. Profile of the Jada®System: the vacuum-induced hemorrhage control device fortreating abnormal postpartum uterine bleeding and postpartumhemorrhage. Expert Rev Med Devices 2021; 18(9):849-853. https://doi.org/10.1080/17434440.2021.1962288

  31. Gilmandyar D, Thornburg LL. Surgical management ofpostpartum hemorrhage. Semin Perinatol 2019; 43(1):27-34. https://doi.org/10.1053/j.semperi.2018.11.006

  32. Henriquez DDCA, Bloemenkamp KWM, van der Bom JG.Management of postpartum hemorrhage: how to improvematernal outcomes? J Thromb Haemost 2018. https://doi.org/10.1111/jth.14200

  33. Federspiel JJ, Eke AC, Eppes CS. Postpartum hemorrhageprotocols and benchmarks: improving care throughstandardization. AJOG 2023; 5(2S): 100740. https://doi.org/10.1016/j.ajogmf.2022.100740

  34. Quezada-Robles A, Quispe-Sarmiento F, Bendezu-Quispe G, etal. Macrosomia and Postpartum Hemorrhagein Latin American and Caribbean Region:Systematic Review and Meta-analysis. Rev BrasGinecol Obstet 2022; 5(11):e706-e723. https://doi.org/10.1055/s-0043-1772597

  35. Brown M, Hong Jr M, Lindquist J. Uterine Artery Embolizationfor Primary Postpartum Hemorrhage. Techniques inVascular and Interventional Radiology 2021; 24(1): 100727.https://doi.org/10.1016/j.tvir.2021.100727




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